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美国退伍军人事务部疼痛诊所阿片类药物使用起始相关因素:一项回顾性研究

Factors Associated with Initiation of Opioid Use in a US Department of Veterans Affairs Pain Clinic: A Retrospective Study.

作者信息

Chen Anderson, Pleasants Erin, Lazatin Justine, Mekdessi Naim, Miller Christopher J, Higgins Diana, Levitt James

机构信息

Department of Geriatric Psychiatry, Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02114, USA.

Department of Psychiatry, Harvard Medical School, 25 Shattuck St., Boston, MA 02115, USA.

出版信息

Brain Sci. 2025 May 7;15(5):491. doi: 10.3390/brainsci15050491.

Abstract

BACKGROUND

Guidelines suggest that, in chronic non-cancer pain (CNCP) management, non-opioid modalities should be prioritized, as there are negative consequences related to opioid use. There is a dearth of literature elucidating the risk factors for initiating opioid use amongst veterans with CNCP.

METHODS

Chart review on 193 patients with a new referral at a local US Department of Veterans Affairs (VA) pain clinic. Patients were required to have CNCP and not be taking opioid medication at the time of referral. The review started on 1 January 2014 and covered the year following. Data were analyzed via stepwise multiple logistic regression using Statistical Analysis System (SAS) software (Version 9.4; SAS institute Inc., Cary, NC, USA).

RESULTS

A total of 37 veterans (19%) received a new opioid prescription in the year following initial encounters at the pain clinic for CNCP. A history of substance use was associated with lower odds of receiving an opioid prescription. In contrast, being employed was associated with higher odds of receiving an opioid prescription.

CONCLUSIONS

Amongst veterans treated for CNCP in a VA pain clinic, a history of substance use and a presence of vocation within the past year prior to presentation are variables associated with the initiation of opioids. Future studies to further elucidate the predictors of opioid prescriptions for CNCP are warranted.

摘要

背景

指南建议,在慢性非癌性疼痛(CNCP)管理中,应优先选择非阿片类治疗方式,因为使用阿片类药物存在不良后果。目前缺乏关于CNCP退伍军人开始使用阿片类药物的风险因素的文献。

方法

对美国当地退伍军人事务部(VA)疼痛诊所193例新转诊患者的病历进行回顾。患者需患有CNCP且在转诊时未服用阿片类药物。回顾从2014年1月1日开始,涵盖随后一年。使用统计分析系统(SAS)软件(版本9.4;SAS研究所,美国北卡罗来纳州卡里)通过逐步多元逻辑回归分析数据。

结果

在疼痛诊所首次就诊后一年中,共有37名退伍军人(19%)接受了新的阿片类药物处方。药物使用史与接受阿片类药物处方的较低几率相关。相比之下,就业与接受阿片类药物处方的较高几率相关。

结论

在VA疼痛诊所接受CNCP治疗的退伍军人中,药物使用史和就诊前一年的就业情况是与开始使用阿片类药物相关的变量。有必要进行进一步研究以阐明CNCP阿片类药物处方的预测因素。

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本文引用的文献

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