Gurrieri Riccardo, Gambini Matteo, Pescini Elena, Mastrogiacomo Diletta, Russomanno Gerardo, Marazziti Donatella
Section of Psychiatry, Department of Clinical and Experimental Medicine, University of Pisa, Via Roma 57, 56100 Pisa, Italy.
Brain Sci. 2025 May 7;15(5):492. doi: 10.3390/brainsci15050492.
Obsessive-compulsive disorder (OCD) is a complex psychiatric condition often associated with alterations in cognitive processes, including memory. Although memory dysfunction has been proposed as a contributing factor to the onset and maintenance of OCD symptoms, it remains debated whether these deficits reflect genuine cognitive impairments or maladaptive metacognitive processes, such as pathological doubt and memory distrust. This review aims to synthesize current findings on memory functioning in OCD, focusing on distinct memory systems and the role of metacognition. A comprehensive literature search was conducted across five databases (PubMed, Scopus, Embase, PsycINFO, and Google Scholar), covering studies up to April 2025. Search terms included "Obsessive-compulsive disorder"; "OCD"; "Memory dysfunction"; "Episodic memory"; "Working memory impairment"; "Prospective memory deficits"; "Checking compulsions"; "Memory confidence"; "Cognitive biases". Short-term memory appears generally preserved in OCD. Working memory deficits are consistently reported, especially in the visuospatial domain, and they are associated with difficulties in updating and clearing irrelevant information. Episodic memory impairments are common and often linked to inefficient encoding strategies and heightened cognitive self-consciousness. Prospective memory is frequently compromised under neutral conditions. Individuals with checking symptoms tend to show intact objective memory performance, despite reporting low memory confidence, supporting the concept of memory distrust. Memory dysfunction in OCD is multifaceted, involving both cognitive and metacognitive alterations. The evidence supports a model in which executive dysfunctions and memory-related beliefs contribute to compulsive behaviors more than objective memory failure. These insights highlight the need for integrative assessment protocols and personalized interventions targeting both cognitive performance and metacognitive appraisals.
强迫症(OCD)是一种复杂的精神疾病,常与包括记忆在内的认知过程改变有关。尽管记忆功能障碍被认为是强迫症症状发作和维持的一个促成因素,但这些缺陷是反映真正的认知障碍还是适应不良的元认知过程,如病理性怀疑和记忆不信任,仍存在争议。本综述旨在综合当前关于强迫症记忆功能的研究结果,重点关注不同的记忆系统和元认知的作用。我们在五个数据库(PubMed、Scopus、Embase、PsycINFO和谷歌学术)中进行了全面的文献检索,涵盖截至2025年4月的研究。检索词包括“强迫症”;“OCD”;“记忆功能障碍”;“情景记忆”;“工作记忆损害”;“前瞻性记忆缺陷”;“检查强迫行为”;“记忆信心”;“认知偏差”。强迫症患者的短期记忆通常似乎未受影响。工作记忆缺陷一直有报道,尤其是在视觉空间领域,并且与更新和清除无关信息的困难有关。情景记忆损害很常见,且往往与低效的编码策略和增强的认知自我意识有关。在中性条件下,前瞻性记忆经常受损。有检查症状的个体尽管报告记忆信心较低,但往往表现出完整的客观记忆表现,这支持了记忆不信任的概念。强迫症中的记忆功能障碍是多方面的,涉及认知和元认知改变。证据支持一种模型,即执行功能障碍和与记忆相关的信念对强迫行为的影响大于客观记忆失败。这些见解凸显了针对认知表现和元认知评估的综合评估方案和个性化干预措施的必要性。