Riepl Hermann Stefan, Santner Viktoria, Schwegel Nora, Hoeller Viktoria, Wallner Markus, Kolesnik Ewald, von Lewinski Dirk, Ablasser Klemens, Kreuzer Philipp, Zorn-Pauly Klaus, Aziz Faisal, Sourij Harald, Zirlik Andreas, Platzer Dieter, Verheyen Nicolas
Division of Cardiology, University Heart Center and Department of Internal Medicine, Medical University of Graz, 8010 Graz, Austria.
Emergency Medicine Unit, Department of Internal Medicine, Medical University of Graz, 8010 Graz, Austria.
Biomedicines. 2025 Apr 27;13(5):1054. doi: 10.3390/biomedicines13051054.
The impact of cold temperature on heart failure (HF) decompensations in continental climate zones is unclear. We aimed to evaluate the association between daily temperature and the subsequent frequency of HF decompensations in an emergency department (ED) in Eastern Austria. A systematic retrospective medical chart review of all admissions to the ED of a tertiary care center within 12 months was conducted. Maximal daily temperature and further meteorological data were obtained from the National Institute for Meteorology and Geodynamics. Among 32.028 ED admissions, there were 1.248 HF decompensations. Median maximal daily temperature ranged from 4.3 °C in January to 28.7 °C in August, and the frequency of decompensations ranged from 65 in August to 143 in January. Maximal daily temperature correlated negatively with the number of decompensations on the subsequent day (beta = -0.07 [95% confidence interval, -0.09 to -0.05], < 0.001). The association remained significant in a multivariate linear regression model adjusted for other meteorological parameters (adjusted beta = -0.07 [-0.10 to -0.04], < 0.001). Moreover, it was present across HF with preserved (n = 375; beta = -0.08 [-0.14 to -0.03], = 0.004) and reduced (n = 331; beta = -0.08 [-0.13 to -0.02], = 0.005) ejection fraction, but not with mildly reduced ejection fraction (n = 160; beta = -0.03 [-0.07 to 0.01], = 0.200). In a European continental climate zone region, lower temperature was associated with a linear increase in subsequent HF decompensations. The sequelae of climate change on HF decompensations may burden healthcare systems in the future and should be systematically investigated in further studies.
在大陆性气候区,低温对心力衰竭(HF)失代偿的影响尚不清楚。我们旨在评估奥地利东部一家急诊科每日温度与随后HF失代偿频率之间的关联。对一家三级护理中心急诊科12个月内的所有入院病例进行了系统的回顾性病历审查。每日最高温度和其他气象数据来自国家气象和地球动力学研究所。在32028例急诊科入院病例中,有1248例HF失代偿。每日最高温度中位数从1月的4.3℃到8月的28.7℃不等,失代偿频率从8月的65例到1月的143例不等。每日最高温度与次日失代偿次数呈负相关(β=-0.07[95%置信区间,-0.09至-0.05],P<0.001)。在针对其他气象参数进行调整的多变量线性回归模型中,这种关联仍然显著(调整后的β=-0.07[-0.10至-0.04],P<0.001)。此外,在射血分数保留(n=375;β=-0.08[-0.14至-0.03],P=0.004)和降低(n=331;β=-0.08[-0.13至-0.02],P=0.005)的HF患者中均存在这种关联,但在射血分数轻度降低(n=160;β=-0.03[-0.07至0.01],P=0.200)的患者中不存在。在欧洲大陆性气候区,较低温度与随后HF失代偿的线性增加相关。气候变化对HF失代偿的后遗症未来可能会给医疗系统带来负担,应在进一步研究中进行系统调查。