实体癌中靶向癌相关成纤维细胞的抗体药物偶联物（ADCs）
CAF-Targeting Antibody-Drug Conjugates (ADCs) in Solid Cancers.
作者信息
Papavassiliou Kostas A, Sofianidi Amalia A, Papavassiliou Athanasios G
机构信息
First University Department of Respiratory Medicine, 'Sotiria' Chest Hospital, Medical School, National and Kapodistrian University of Athens, 11527 Athens, Greece.
Department of Biological Chemistry, Medical School, National and Kapodistrian University of Athens, 11527 Athens, Greece.
出版信息
Cancers (Basel). 2025 May 14;17(10):1654. doi: 10.3390/cancers17101654.
Abstract
The tumor microenvironment (TME) constitutes a major part of solid malignancies and within it, cancer-associated fibroblasts (CAFs) continuously interact with cancer cells, fostering their growth and survival [...].
摘要
肿瘤微环境（TME）是实体恶性肿瘤的主要组成部分，在肿瘤微环境中，癌症相关成纤维细胞（CAF）持续与癌细胞相互作用，促进癌细胞的生长和存活 [...]。
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