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使用欧洲癌症研究与治疗组织核心生活质量问卷(EORTC QLQ - 30)和CX24对阿联酋宫颈癌女性生活质量的研究:阿联酋的初步观察。

Quality of Life of Emirati Women with Cervical Cancer Using EORTC QLQ-30 and CX24: A First Look in the UAE.

作者信息

Smail Linda

机构信息

College of Interdisciplinary Studies, Zayed University, Dubai 19282, United Arab Emirates.

出版信息

Int J Environ Res Public Health. 2025 Apr 24;22(5):671. doi: 10.3390/ijerph22050671.

Abstract

BACKGROUND

Cervical cancer is the fourth leading cause of cancer-related mortality among women globally and remains a prevalent malignancy among Emirati women. This study assessed the quality of life of Emirati women with cervical cancer and identified key factors influencing their well-being to inform targeted interventions.

METHODS

A cross-sectional study was conducted among 72 Emirati women diagnosed with cervical cancer utilizing the Arabic-translated European Organization for Research and Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ-C30 and QLQ-CX24). Sociodemographic and clinical data were collected. Statistical analyses included ANOVA, independent-sample -tests, and, where assumptions were violated, Kruskal-Wallis and Mann-Whitney tests.

RESULTS

The mean global health status/QoL score was 64.4 (SD ± 20.4), indicating moderate well-being. The cognitive (69.9 ± 23.5) and role functioning (65.1 ± 25.0) scores were relatively high, whereas the social functioning score was lower (61.8 ± 25.2). Fatigue (41.5 ± 27.5), sleep disturbance (40.7 ± 31.3), and pain (39.4 ± 27.6) were the most prevalent symptoms. Radiotherapy negatively impacted sexual enjoyment ( = 0.019), whereas lower income and metastases were associated with worse symptom burden. Higher education, employment, and physical activity correlated positively with functional well-being.

CONCLUSIONS

Early-stage diagnosis, financial stability, and physical activity were key predictors of better QoL. Addressing financial disparities, managing symptoms, and improving survivorship care are essential.

摘要

背景

宫颈癌是全球女性癌症相关死亡的第四大主要原因,在阿联酋女性中仍然是一种普遍的恶性肿瘤。本研究评估了阿联酋宫颈癌女性的生活质量,并确定了影响其幸福感的关键因素,以为针对性干预提供依据。

方法

对72名被诊断为宫颈癌的阿联酋女性进行了一项横断面研究,采用阿拉伯语翻译的欧洲癌症研究与治疗组织生活质量问卷(EORTC QLQ-C30和QLQ-CX24)。收集了社会人口统计学和临床数据。统计分析包括方差分析、独立样本t检验,以及在假设不成立时使用的克鲁斯卡尔-沃利斯检验和曼-惠特尼检验。

结果

全球健康状况/生活质量平均得分为64.4(标准差±20.4),表明幸福感中等。认知(69.9±23.5)和角色功能(65.1±25.0)得分相对较高,而社会功能得分较低(61.8±25.2)。疲劳(41.5±27.5)、睡眠障碍(40.7±31.3)和疼痛(39.4±27.6)是最常见的症状。放疗对性快感有负面影响(P = 0.019),而较低的收入和转移与更严重的症状负担相关。高等教育、就业和体育活动与功能幸福感呈正相关。

结论

早期诊断、经济稳定和体育活动是生活质量较好的关键预测因素。解决经济差距、管理症状和改善生存护理至关重要。

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