Arumugam T, Sohal G S
Exp Neurol. 1985 Oct;90(1):281-6. doi: 10.1016/0014-4886(85)90063-9.
We conducted a quantitative study of the trochlear motoneurons and the myotube clusters in the corresponding superior oblique muscle of the Japanese quail, before, during, and after the period of normally occurring motoneuron degeneration. A ratio of approximately 1:1 between myotube clusters and neurons was observed at the onset of motoneuron degeneration. The number of myotube clusters prior to neuron death was 37% greater than the number of neurons surviving after cell death. These results are in contradiction with the hypothesis that the number of myotube clusters is the deciding factor for the survival of motoneurons during the critical stages of development.
我们对日本鹌鹑正常发生运动神经元退化期间及前后，其滑车运动神经元和相应上斜肌中的肌管簇进行了定量研究。在运动神经元退化开始时，观察到肌管簇与神经元的比例约为1:1。神经元死亡前的肌管簇数量比细胞死亡后存活的神经元数量多37%。这些结果与以下假设相矛盾：在发育的关键阶段，肌管簇的数量是运动神经元存活的决定性因素。
