在人类精子中发现一种含γ-羧基谷氨酸的蛋白质。
Discovery of a gamma-carboxyglutamic acid-containing protein in human spermatozoa.
作者信息
Soute B A, Müller-Esterl W, de Boer-van den Berg M A, Ulrich M, Vermeer C
出版信息
FEBS Lett. 1985 Oct 7;190(1):137-41. doi: 10.1016/0014-5793(85)80444-0.
PMID:4043391
Abstract
Here we describe the identification of a gamma-carboxyglutamic acid-containing protein in human spermatozoa. After thermal decarboxylation the protein is a good substrate for vitamin K-dependent carboxylase from various origins. A quick purification procedure for the decarboxylated protein is presented and in a preliminary characterization we have established its Mr (28 000-30 000) and its amino acid composition.
摘要
在此，我们描述了在人类精子中鉴定出一种含γ-羧基谷氨酸的蛋白质。热脱羧后，该蛋白质是来自各种来源的维生素K依赖性羧化酶的良好底物。本文介绍了一种对脱羧蛋白的快速纯化方法，并且在初步表征中，我们确定了其分子量（28000 - 30000）及其氨基酸组成。
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