• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

[胃平滑肌细胞中的钙电流与机电偶联]

[Calcium current and electromechanical coupling in the smooth muscle cells of the stomach].

作者信息

Rekalov V V, Taranenko V M, Shuba M F

出版信息

Fiziol Zh SSSR Im I M Sechenova. 1985 Jul;71(7):896-903.

PMID:4043429
Abstract

The relationship between inward current and contraction was studied with double sucrose gap technique and measurement of contraction of the small muscular bundle in circular muscle from the fundus of guinea pig stomach. In voltage-clamped circular muscle, an inward current observed during depolarizing potential step was sensitive to Cd2+ or low external Ca2+ and had two components: a transient and a steady-state ones. Inactivation of this current was both voltage-dependent and Ca-current-dependent. Transient inward current activated phasic contraction, while the steady-state current activated tonic contraction. The voltage--dependence of the steady-state inward current was estimated with the Hodgkin--Huxley equation.

摘要

采用双蔗糖间隙技术和豚鼠胃底环行肌小肌束收缩测量法,研究内向电流与收缩之间的关系。在电压钳制的环行肌中,去极化电位阶跃期间观察到的内向电流对Cd2+或低细胞外Ca2+敏感,并有两个成分:一个瞬态成分和一个稳态成分。该电流的失活既依赖电压又依赖钙电流。瞬态内向电流激活相性收缩,而稳态电流激活紧张性收缩。用霍奇金-赫胥黎方程估算稳态内向电流的电压依赖性。

相似文献

1
[Calcium current and electromechanical coupling in the smooth muscle cells of the stomach].[胃平滑肌细胞中的钙电流与机电偶联]
Fiziol Zh SSSR Im I M Sechenova. 1985 Jul;71(7):896-903.
2
Role of intracellular calcium in the phasic and tonic contractions of stomach smooth muscles.细胞内钙在胃平滑肌相性和紧张性收缩中的作用
Acta Physiol Pharmacol Bulg. 1978;4(3):12-20.
3
Effects of different kinds of stretch on voltage-dependent calcium current in antrial circular smooth muscle cells of the guinea-pig.
Sheng Li Xue Bao. 2000 Feb;52(1):69-74.
4
Inward calcium currents in cultured and freshly isolated detrusor muscle cells: evidence of a T-type calcium current.培养的和新鲜分离的逼尿肌细胞中的内向钙电流:T型钙电流的证据。
J Urol. 2001 Feb;165(2):621-6. doi: 10.1097/00005392-200102000-00084.
5
Membrane potential and excitation-contraction coupling in smooth muscle.平滑肌的膜电位与兴奋-收缩偶联
Fed Proc. 1982 Oct;41(12):2879-82.
6
Effects of nitric oxide donors, S-nitroso-L-cysteine and sodium nitroprusside, on the whole-cell and single channel currents in single myocytes of the guinea-pig proximal colon.一氧化氮供体S-亚硝基-L-半胱氨酸和硝普钠对豚鼠近端结肠单个肌细胞全细胞电流和单通道电流的影响。
Br J Pharmacol. 1998 Feb;123(3):505-17. doi: 10.1038/sj.bjp.0701605.
7
Voltage clamp simulations for multifiber bundles in a double sucrose gap: cable complications.双蔗糖间隙中多纤维束的电压钳模拟:电缆复杂性
Gen Physiol Biophys. 1986 Oct;5(5):449-71.
8
[Mechanisms of change in the tonus of depolarized smooth muscle (guinea pig taenia coli) during application of a hyperpolarizing current].
Biofizika. 1976 Sep-Oct;21(5):856-61.
9
Evidence that a Ca2+ sparks/STOCs coupling mechanism is responsible for the inhibitory effect of caffeine on electro-mechanical coupling in guinea pig ureteric smooth muscle.有证据表明,Ca2+火花/自发性瞬态外向电流(STOCs)偶联机制是咖啡因对豚鼠输尿管平滑肌电-机械偶联产生抑制作用的原因。
Cell Calcium. 2007 Sep;42(3):303-11. doi: 10.1016/j.ceca.2006.12.005. Epub 2007 Feb 12.
10
[Coupling of electrical processes on the membrane to the contractile activity of anococcygeus smooth muscle cells].[膜上电过程与肛门尾骨肌平滑肌细胞收缩活动的耦合]
Biull Eksp Biol Med. 1980 Apr;89(4):392-5.