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在椎间孔镜下腰椎间盘切除术中保护黄韧带可减少硬膜外纤维化形成。

Protection of the ligamentum flavum reduces epidural fibrosis formation in endoscopic lumbar discectomy.

作者信息

Merter Abdullah, Bozkurt Orhun Eray, Dolas Ilyas, Peker Elif, Unal Sena, Sahin Duran, Dumlupinar Ebru

机构信息

Ankara University Faculty of Medicine, Ankara, Turkey.

Kulu State Hospital, Konya, Turkey.

出版信息

Eur Spine J. 2025 May 28. doi: 10.1007/s00586-025-08960-4.


DOI:10.1007/s00586-025-08960-4
PMID:40434580
Abstract

PURPOSE: Lumbar disc herniation is a prevalent condition that leads to lower back pain, weakness, and claudication. While microdiscectomy has long been the gold standard for surgical treatment, advances in technology have introduced endoscopic techniques, such as Unilateral Biportal Endoscopic spine surgery. Despite these advances, epidural fibrosis remains a common complication that, potentially hinders recovery and complicating revision surgeries. This study aimed to compare the extent of epidural fibrosis between microdiscectomy and UBE surgery with preserved flavum and flavectomy. METHODS: This retrospective study included 47 patients diagnosed with lumbar disc herniation who underwent surgery between August 2020 and July 2022 at two tertiary university hospitals. The patients underwent endoscopic surgery with flavum preservation (n = 16), flavum excision (n = 16), lumbar microdiscectomy with flavectomy (n = 15). Preoperative and postoperative imaging, including X-rays, computed tomography, and magnetic resonance imaging were performed. Functional scores (Visual Analog Scale, Japanese Orthopedic Association score, and Oswestry Disability Index were assessed. Postoperative magnetic resonance imaging was conducted at three months to evaluate epidural fibrosis. RESULTS: The rate of epidural fibrosis was significantly lower in the flavum sparing UBE (0.18 ± 0.17) compared to the flavum non-sparring UBE (0.38 ± 0.19) and the flavum non-sparring microdiscectomy (0.47 ± 0.18) (p < 0.001). Functional scores significantly improved postoperatively in all groups, with significant differences noted in JOA, Oswestry, and VAS scores (p < 0.01). Early functional score differences between the groups were found to be significant in favor of UBE, particularly in the flavum-sparing group. CONCLUSION: The preservation of flavum during UBE surgery leads to significantly less epidural fibrosis compared to both flavum non-sparring UBE and microdiscectomy. Functional improvements were similar across groups, but flavum sparring UBE surgery demonstrated better early postoperative outcomes. The results suggest that preserving flavum during endoscopic spine surgery may reduce epidural fibrosis formation and promote better recovery, supporting the benefits of minimally invasive techniques in lumbar disc herniation surgery.

摘要

目的:腰椎间盘突出症是一种常见疾病,可导致下背部疼痛、无力和间歇性跛行。虽然显微椎间盘切除术长期以来一直是手术治疗的金标准,但技术的进步引入了内镜技术,如单侧双通道内镜脊柱手术。尽管有这些进展,但硬膜外纤维化仍然是一种常见的并发症,可能会阻碍恢复并使翻修手术复杂化。本研究旨在比较显微椎间盘切除术与保留黄韧带和切除黄韧带的UBE手术之间硬膜外纤维化的程度。 方法:这项回顾性研究纳入了47例在2020年8月至2022年7月期间于两家三级大学医院接受手术的腰椎间盘突出症患者。患者接受了保留黄韧带的内镜手术(n = 16)、切除黄韧带的内镜手术(n = 16)、切除黄韧带的腰椎显微椎间盘切除术(n = 15)。进行了术前和术后影像学检查,包括X线、计算机断层扫描和磁共振成像。评估了功能评分(视觉模拟量表、日本骨科协会评分和Oswestry功能障碍指数)。术后三个月进行磁共振成像以评估硬膜外纤维化。 结果:与不保留黄韧带的UBE手术(0.38±0.19)和不保留黄韧带的显微椎间盘切除术(0.47±0.18)相比,保留黄韧带的UBE手术中硬膜外纤维化的发生率显著更低(0.18±0.17)(p < 0.001)。所有组术后功能评分均显著改善,在日本骨科协会评分、Oswestry评分和视觉模拟量表评分方面存在显著差异(p < 0.01)。发现各组之间早期功能评分差异对UBE手术有利,特别是在保留黄韧带的组中。 结论:与不保留黄韧带的UBE手术和显微椎间盘切除术相比,UBE手术中保留黄韧带可显著减少硬膜外纤维化。各组功能改善情况相似,但保留黄韧带的UBE手术术后早期效果更好。结果表明,在内镜脊柱手术中保留黄韧带可能会减少硬膜外纤维化的形成并促进更好的恢复,支持了微创技术在腰椎间盘突出症手术中的益处。

相似文献

[1]
Protection of the ligamentum flavum reduces epidural fibrosis formation in endoscopic lumbar discectomy.

Eur Spine J. 2025-5-28

[2]
Ligamentum Flavum Flap Technique in Lumbar Microdiscectomy.

JBJS Essent Surg Tech. 2024-11-8

[3]
Unilateral Biportal Endoscopy for Lumbar Spinal Stenosis and Lumbar Disc Herniation.

JBJS Essent Surg Tech. 2023-6-27

[4]
Revisiting Ligament-Sparing Lumbar Microdiscectomy: When to Preserve Ligamentum Flavum and How to Evaluate Radiological Results for Epidural Fibrosis.

World Neurosurg. 2018-6

[5]
Comparison of full-endoscopic foraminoplasty and lumbar discectomy (FEFLD), unilateral biportal endoscopic (UBE) discectomy, and microdiscectomy (MD) for symptomatic lumbar disc herniation.

Eur Spine J. 2023-2

[6]
Comparison of surgical outcomes between unilateral biportal endoscopic technique and open microdiscectomy in patients with single-level lumbar disc herniation: a single-center retrospective study in China.

Asian Spine J. 2025-8

[7]
Comparative study of the learning curves for percutaneous endoscopic interlaminar lumbar discectomy and unilateral biportal endoscopy techniques.

BMC Surg. 2025-5-15

[8]
Clinical comparison of unilateral biportal endoscopic technique versus open microdiscectomy for single-level lumbar discectomy: a multicenter, retrospective analysis.

J Orthop Surg Res. 2018-1-31

[9]
Comparison of lumbar microdiscectomy and unilateral biportal endoscopic discectomy outcomes: a single-center experience.

J Neurosurg Spine. 2024-3-1

[10]
The clinical efficacy of biportal endoscopy is comparable to that of uniportal endoscopy the interlaminar approach for the treatment of L5/S1 lumbar disc herniation.

Front Surg. 2022-9-27

本文引用的文献

[1]
Unilateral biportal endoscopic discectomy versus microdiscectomy for lumbar disc herniation: a systematic review and meta-analysis.

Eur Spine J. 2024-6

[2]
Comparison of lumbar microdiscectomy and unilateral biportal endoscopic discectomy outcomes: a single-center experience.

J Neurosurg Spine. 2024-3-1

[3]
Efficacy and safety of unilateral biportal endoscopy versus other spine surgery: A systematic review and meta-analysis.

Front Surg. 2022-7-25

[4]
The Learning Curve of Unilateral Biportal Endoscopic (UBE) Spinal Surgery by CUSUM Analysis.

Front Surg. 2022-4-29

[5]
The Preventive Effect of Decorin on Epidural Fibrosis and Epidural Adhesions After Laminectomy.

Front Pharmacol. 2021-12-16

[6]
Postoperative Epidural Fibrosis Prevention: Which Is Better-Autologous Fat versus Gelfoam.

Asian Spine J. 2022-6

[7]
An Evidence Based Review of Epidurolysis for the Management of Epidural Adhesions.

Psychopharmacol Bull. 2020-10-15

[8]
A new classification for spinal epidural hematoma following microendoscopic decompressive laminotomy: A prospective clinical and magnetic resonance imaging study of 245 patients.

Acta Orthop Traumatol Turc. 2020-11

[9]
Unilateral biportal endoscopic decompression for degenerative lumbar canal stenosis.

J Spine Surg. 2020-6

[10]
The benefit zone of full-endoscopic spine surgery.

J Spine Surg. 2019-6

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