Blank A A, Schnyder U W
Dermatologica. 1985;171(2):89-94. doi: 10.1159/000249398.
The therapeutic results obtained with soft-X-ray irradiation on 77 lesions in 52 patients are reported. 35 males (67.3%) and 17 females (32.7%) were treated. Clinical and histological features revealed Bowen's disease in 73 cases (94.8%) and erythroplasia of Queyrat in 4 cases (5.2%). The primary healing was rated as 100% in all cases up to 6 months after a cumulative dosage of 3,200-5,000 R. 2 cases with a genital localization (2.6% of all sites and 11.1% of anogenital localizations) relapsed after 8 and 16 months, respectively. The follow-up period ranged from 1 to 11 years with a mean of 3 years. In order not to miss the late recurrences, the oncologic follow-up is taken care of by the Dermatology Department of the Zurich University Hospital during 10 years, or longer in some cases. Association with a malignant internal tumour (larynx, bronchi, anus) was found in 3 patients (5.8%).
报告了对52例患者的77处病变进行软X线照射的治疗结果。接受治疗的男性35例（67.3%），女性17例（32.7%）。临床和组织学特征显示，73例（94.8%）为鲍温病，4例（5.2%）为凯腊增殖性红斑。在累积剂量达3200 - 5000伦琴后，所有病例在6个月内的一期愈合率均为100%。2例发生于生殖器部位的病变（占所有部位的2.6%，占肛门生殖器部位的11.1%）分别在8个月和16个月后复发。随访期为1至11年，平均3年。为了不遗漏晚期复发，苏黎世大学医院皮肤科负责长达10年或更长时间（某些情况下）的肿瘤学随访。3例患者（5.8%）伴有恶性内部肿瘤（喉、支气管、肛门）。
