Di Pasquale G, Pinelli G, Manini G L, Lusa A M, Tencati R, Andreoli A, Fagioli L, Limoni P
G Ital Cardiol. 1985 Apr;15(4):407-13.
Many cardiac disorders can cause acute cerebrovascular insufficiency. The spectrum of potentially embolic cardiac conditions is wide; early recognition may determine a definite change in the management and prognosis of patients. In recent years the relevance of echocardiography in the screening of patients with cerebral ischemia has been emphasized. In order to identify potentially embolic cardiac conditions, 180 consecutive non selected patients with cerebrovascular insufficiency, underwent a clinical cardiological evaluation and an echocardiogram. The study population included 132 men and 48 women; the mean age was 51.7 years (range 19 to 72 years). A technically adequate echocardiogram was obtained in 153 patients. In 131 patients echocardiography was negative; cardiac lesions were detected in 22 patients (14.4%): mitral stenosis in 2, calcified aortic stenosis in 1, valvular endocarditis vegetations in 3, dilatative cardiomyopathy in 2, hypertrophic cardiomyopathy in 4, mitral valve prolapse in 4, regional left ventricular diskynesia in 5, mitral anulus calcification in 1. Patients were divided into 3 groups according to the results of cerebral angiography: 68 patients with normal angiography (Group I), 54 patients with atheromasic lesions on cerebral angiography (Group II), 31 patients in whom cerebral angiography was not performed (Group III). A higher incidence of cardiac diseases was found in the patients of Group I. The lack of lesions on cerebral angiography and the presence of embolic high-risk cardiac conditions strengthened a causal relationship of the cardiac disorder with cerebrovascular insufficiency in 10 of the 23 patients. In the mean follow-up period of 18 months of these 10 patients who underwent cardiac surgery or anticoagulation, no further attacks of cerebrovascular insufficiency were observed.(ABSTRACT TRUNCATED AT 250 WORDS)
许多心脏疾病可导致急性脑血管供血不足。潜在的栓塞性心脏疾病范围广泛;早期识别可能决定患者治疗和预后的明确变化。近年来,超声心动图在脑缺血患者筛查中的相关性得到了强调。为了识别潜在的栓塞性心脏疾病,180例连续入选的非选择性脑血管供血不足患者接受了临床心脏评估和超声心动图检查。研究人群包括132名男性和48名女性;平均年龄为51.7岁(范围19至72岁)。153例患者获得了技术上足够的超声心动图。131例患者超声心动图检查为阴性;22例患者(14.4%)检测到心脏病变:二尖瓣狭窄2例,钙化性主动脉瓣狭窄1例,瓣膜性心内膜炎赘生物3例,扩张型心肌病2例,肥厚型心肌病4例,二尖瓣脱垂4例,局部左心室运动障碍5例,二尖瓣环钙化1例。根据脑血管造影结果将患者分为3组:68例脑血管造影正常的患者(I组),54例脑血管造影有动脉粥样硬化病变的患者(II组),31例未进行脑血管造影的患者(III组)。I组患者中心脏疾病的发生率较高。在23例患者中的10例中,脑血管造影无病变且存在栓塞高危心脏疾病,这加强了心脏疾病与脑血管供血不足之间的因果关系。在这10例接受心脏手术或抗凝治疗的患者平均18个月的随访期内,未观察到进一步的脑血管供血不足发作。(摘要截短于250字)