血管紧张素II对虹鳟鱼（Salmo gairdneri）肾脏和心血管系统的影响。

Renal and cardiovascular effects of angiotensin II in the rainbow trout, Salmo gairdneri.

作者信息

Gray C J, Brown J A

出版信息

Gen Comp Endocrinol. 1985 Sep;59(3):375-81. doi: 10.1016/0016-6480(85)90394-6.

Abstract

The renal and cardiovascular effects of an intravenous infusion of angiotensin II in the freshwater anaesthetised rainbow trout, Salmo gairdneri, have been reappraised, without the infusion of noradrenaline. In these fish the previously reported antidiuretic response to angiotensin II was not maintained although a systemic pressor response persisted and the tubular transport maximum for glucose remained depressed. The data suggest that angiotensin has an intrarenal action which may play a role in renal adaptation to increased environmental salinities.

摘要

在未输注去甲肾上腺素的情况下，重新评估了静脉输注血管紧张素II对淡水麻醉的虹鳟（Salmo gairdneri）的肾脏和心血管效应。在这些鱼中，尽管全身升压反应持续存在且葡萄糖的肾小管转运最大值仍然降低，但先前报道的对血管紧张素II的抗利尿反应并未维持。数据表明，血管紧张素具有肾内作用，可能在肾脏适应环境盐度增加中发挥作用。