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面部痤疮疤痕对生活质量、焦虑、抑郁的影响及其相关危险因素。

The impact of facial acne scars on quality of life, anxiety, depression and its associated risk factors.

作者信息

Heah M M, Low D W, Ng R S, Mohd Ali N, Jamil A

机构信息

Hospital Pulau Pinang, Department of Dermatology, Georgetown, Penang, Malaysia.

Clinical Research Centre, Hospital Pulau Pinang, Georgetown, Penang, Malaysia.

出版信息

Med J Malaysia. 2025 May;80(3):313-320.

Abstract

INTRODUCTION

Acne scars negatively impact psychosocial and emotional wellbeing. However, data on the impact of acne scarring on anxiety and depression as well as quality of life are limited. This study assessed the effects of facial acne scars on quality of life, anxiety, and depression, and identifies risk factors associated with scar severity.

MATERIALS AND METHODS

We conducted an observational cross-sectional study between February 2023 and January 2024 at dermatology clinics in two public hospitals. A total of 175 patients with facial acne scars were recruited. Data collection included patient demographics, acne severity, scar severity (SCAR-S) and questionnaires such as Dermatology Life Quality Index (DLQI) and Hospital Anxiety and Depression Scale (HADS). The association between scar severity, quality of life, anxiety, and depression was analyzed using Chi-square tests and ordinal logistic regression.

RESULTS

The median age of participants was 26.9 years and 56% were female. Most patients had mild (37.7%) to moderate (28.6%) acne scars. Among patients with severe/very severe scars, 69.2% reported a significant impact on quality of life (DLQI>10). A significant association was observed between scar severity and anxiety (p=0.009) as well as depression (p<0.001). There was a positive correlation between HADS and DLQI scores (r=0.602, p<0.001). Delayed or absent treatment after acne onset was a significant risk factor for acne scar severity.

CONCLUSION

Facial acne scars are associated with impairment in quality of life and increased anxiety and depression. Timely and effective acne treatment is essential to reduce the severity of scarring and its psychosocial burden.

摘要

引言

痤疮疤痕会对心理社会和情绪健康产生负面影响。然而,关于痤疮疤痕对焦虑、抑郁以及生活质量影响的数据有限。本研究评估了面部痤疮疤痕对生活质量、焦虑和抑郁的影响,并确定了与疤痕严重程度相关的风险因素。

材料与方法

我们于2023年2月至2024年1月在两家公立医院的皮肤科诊所进行了一项观察性横断面研究。共招募了175名面部有痤疮疤痕的患者。数据收集包括患者人口统计学信息、痤疮严重程度、疤痕严重程度(SCAR-S)以及皮肤病生活质量指数(DLQI)和医院焦虑抑郁量表(HADS)等问卷。使用卡方检验和有序逻辑回归分析疤痕严重程度、生活质量、焦虑和抑郁之间的关联。

结果

参与者的中位年龄为26.9岁,56%为女性。大多数患者有轻度(37.7%)至中度(28.6%)痤疮疤痕。在有重度/极重度疤痕的患者中,69.2%报告生活质量受到显著影响(DLQI>10)。观察到疤痕严重程度与焦虑(p = 0.009)以及抑郁(p<0.001)之间存在显著关联。HADS与DLQI评分之间存在正相关(r = 0.602,p<0.001)。痤疮发作后治疗延迟或未治疗是痤疮疤痕严重程度的一个重要风险因素。

结论

面部痤疮疤痕与生活质量受损以及焦虑和抑郁增加有关。及时有效的痤疮治疗对于减轻疤痕严重程度及其心理社会负担至关重要。

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