Tamargo María, Gutiérrez Enrique, Carreño Jorge García, Álvarez María Eugenia Vázquez, Sanz-Ruiz Ricardo, Huanca Mike, Ludeña Erika, Soriano Javier, Elízaga Jaime, Fernández-Avilés Francisco, Bermejo Javier
Departamento de Cardiología, Hospital General Universitario Gregorio Marañón, Instituto de Investigación Sanitaria Gregorio Marañón, Madrid, España Departamento de Cardiología Hospital General Universitario Gregorio Marañón Instituto de Investigación Sanitaria Gregorio Marañón Madrid España.
Facultad de Medicina, Universidad Complutense de Madrid, Madrid, España Facultad de Medicina Universidad Complutense de Madrid Madrid España.
REC Interv Cardiol. 2025 Mar 11;7(2):82-90. doi: 10.24875/RECIC.M24000497. eCollection 2025 Apr-Jun.
Because of the potential need for permanent pacemaker implantation, patients are frequently monitored for days after transcatheter aortic valve implantation (TAVI), particularly when using self-expanding valves. We sought to determine whether the appearance and management of conduction disturbances after TAVI can be improved by combining the cusp overlap projection (COP) and a rapid atrial pacing (RAP) protocol to detect the need for pacemaker implantation.
We consecutively studied a total of 273 patients who underwent TAVI with self-expanding valves from 2018 through 2022 (134 undergoing standard implantations and 139 COP + RAP). Assessment included the 90-day follow-up.
Complete heart block was reported in 25.4% and 14.4% in the standard-of-care and COP + RAP group, with a marked decrease in transient atrioventricular block (12.8% vs 2.9%, respectively; = .007). The absence of the Wenckebach phenomenon during RAP had a negative predictive value of 97% (95%CI, 91-99) for pacemaker implantation at the follow-up, which significantly decreased the need for 24-hour temporary pacemaker monitoring in the COP + RAP group (91.8% vs 28.1%; < .0001) and the median [IQR] length of stay (5.0 [4-8] days vs 2.0 [1-4] days; < .0001). At the 90-day follow-up, COP + RAP reduced pacemaker implantation (OR, 0.48; 95%CI, 0.24-0.92; = .031), as well as the risk of infection-related readmissions significantly (OR, 0.35; 95%CI, 0.12-0.89; = .036).
The combination of COP + RAP during self-expanding TAVI improves postoperative screening for conduction disturbances, thus reducing the need for cardiac rhythm monitoring, and the length stay. The COP + RAP strategy improves the short-term clinical outcomes of self-expanding TAVI due to fewer infection-related readmissions.
由于经导管主动脉瓣植入术(TAVI)后可能需要永久起搏器植入,尤其是在使用自膨胀瓣膜时,患者在术后常需接受数天的监测。我们试图确定,通过结合瓣叶重叠投影(COP)和快速心房起搏(RAP)方案来检测起搏器植入需求,能否改善TAVI后传导障碍的表现及管理。
我们连续研究了2018年至2022年间共273例行自膨胀瓣膜TAVI的患者(134例行标准植入术,139例行COP + RAP)。评估包括90天随访。
标准治疗组和COP + RAP组分别有25.4%和14.4%的患者发生完全性心脏传导阻滞,短暂性房室传导阻滞显著减少(分别为12.8%和2.9%;P = 0.007)。RAP期间无文氏现象对随访时起搏器植入的阴性预测值为97%(95%CI,91 - 99),这显著减少了COP + RAP组24小时临时起搏器监测的需求(91.8%对28.1%;P < 0.0001)以及中位[IQR]住院时间(5.0[4 - 8]天对2.0[1 - 4]天;P < 0.0001)。在90天随访时,COP + RAP减少了起搏器植入(OR,0.48;95%CI,0.24 - 0.92;P = 0.031),以及与感染相关再入院的风险(OR,0.35;95%CI,0.12 - 0.89;P = 0.036)。
自膨胀TAVI期间采用COP + RAP可改善术后传导障碍筛查,从而减少心律监测需求和住院时间。由于与感染相关的再入院减少,COP + RAP策略改善了自膨胀TAVI的短期临床结局。