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一名年轻男性类风湿关节炎合并格雷夫斯病的挑战性管理:病例报告

The Challenging Management of Rheumatoid Arthritis Overlapping With Graves' Disease in a Young Male: A Case Report.

作者信息

Hamsho Suaad, Aldolly Ahmed, Alaswad Mohammed

机构信息

Rheumatology Department, Faculty of Medicine Damascus University Damascus Syria.

Faculty of Medicine Hama University Hama Syria.

出版信息

Clin Case Rep. 2025 May 27;13(6):e70540. doi: 10.1002/ccr3.70540. eCollection 2025 Jun.

Abstract

Autoimmune disorders occur when the body's immune system mistakenly attacks its own tissues. Generally, these disorders are more prevalent in female patients. The presence of one autoimmune disease can alter the immune system's balance, making the individual more susceptible to developing other autoimmune conditions. Rheumatoid arthritis and Graves' disease are two examples of autoimmune conditions that can overlap in the same patient. In this case report, we present a unique scenario of a male patient initially exhibiting symptoms suggestive of gravis' disease. The subsequent emergence of signs and symptoms of rheumatoid arthritis further complicated the situation. This overlapping presentation posed significant challenges in managing his condition and balancing the treatment regimens for both conditions while minimizing potential drug interactions and adverse effects.

摘要

自身免疫性疾病是指人体免疫系统错误地攻击自身组织时发生的疾病。一般来说,这些疾病在女性患者中更为普遍。一种自身免疫性疾病的存在会改变免疫系统的平衡,使个体更容易患上其他自身免疫性疾病。类风湿性关节炎和格雷夫斯病是两种可能在同一患者身上重叠的自身免疫性疾病的例子。在本病例报告中,我们呈现了一名男性患者的独特病例,该患者最初表现出提示格雷夫斯病的症状。随后出现的类风湿性关节炎的体征和症状使情况更加复杂。这种重叠表现给治疗他的病情以及平衡两种疾病的治疗方案带来了重大挑战,同时要尽量减少潜在的药物相互作用和不良反应。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/658d/12107596/fb6512c86ff6/CCR3-13-e70540-g001.jpg

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