Lai-Kwon Julia, Rutherford Claudia, Jefford Michael, Zhang Iris, Devereux Catherine, Herath Dishan, Burbury Kate, Best Stephanie
Department of Medical Oncology, Peter MacCallum Cancer Centre, Melbourne, Australia.
Department of Health Services Research, Peter MacCallum Cancer Centre, Melbourne, Australia.
Qual Life Res. 2025 May 29. doi: 10.1007/s11136-025-03995-y.
Real-time electronic patient-reported outcome (ePRO) symptom monitoring is a complex intervention with few examples of successful implementation at scale. A key challenge is designing a clear ePRO symptom monitoring workflow to support implementation into practice. We aimed to create an empirical and theory-informed site-specific workflow guided by the Action, Actor, Context, Target, Time (AACTT) implementation science framework.
A five-step process was undertaken to customize a generic ePRO symptom monitoring workflow to create a site-specific version: (1) design a generic ePRO symptom monitoring workflow through a qualitative study with key stakeholders; (2) conduct co-design workshops to understand stakeholder preferences regarding a site-specific version; (3) code co-design workshop data using the AACTT framework to produce a provisional site-specific version; (4) conduct a final co-design workshop using the AACTT framework to finalize stakeholder preferences for a site-specific version; and (5) code co-design workshop data using the AACTT framework to produce a final site-specific version.
Participants (n = 27) included nine patients, four caregivers, four oncologists, four nurses, two pharmacists, two clinic administrators, and two Electronic Medical Record (EMR) analysts. Provisional and final site-specific workflows were generated outlining the key AACTT components for each step of ePRO symptom monitoring.
We demonstrated the value in using the AACTT to guide the co-design of a site-specific workflow for ePRO symptom monitoring. By describing this process in detail, we will enable others to replicate this process for creating site-specific workflows not only for ePRO symptom monitoring, but for any complex clinical process.
实时电子患者报告结局(ePRO)症状监测是一项复杂的干预措施,很少有大规模成功实施的实例。一个关键挑战是设计清晰的ePRO症状监测工作流程以支持在实践中的实施。我们旨在创建一个以行动、行动者、背景、目标、时间(AACTT)实施科学框架为指导的基于实证和理论的特定场所工作流程。
采取了一个五步流程来定制通用的ePRO症状监测工作流程以创建特定场所版本:(1)通过与关键利益相关者的定性研究设计通用的ePRO症状监测工作流程;(2)举办联合设计研讨会以了解利益相关者对特定场所版本的偏好;(3)使用AACTT框架对联合设计研讨会数据进行编码以生成临时的特定场所版本;(4)使用AACTT框架举办最终联合设计研讨会以确定利益相关者对特定场所版本的偏好;(5)使用AACTT框架对联合设计研讨会数据进行编码以生成最终的特定场所版本。
参与者(n = 27)包括9名患者、4名护理人员、4名肿瘤学家、4名护士、2名药剂师、2名诊所管理人员和2名电子病历(EMR)分析师。生成了临时和最终的特定场所工作流程,概述了ePRO症状监测每个步骤的关键AACTT组件。
我们证明了使用AACTT指导ePRO症状监测特定场所工作流程联合设计的价值。通过详细描述这个过程,我们将使其他人能够复制这个过程,不仅为ePRO症状监测,也为任何复杂的临床过程创建特定场所工作流程。