Jorgenson Laura C, Wang Sherry S, Grotz Travis E, Graham Rondell P, Navin Patrick J, Favazza Christopher, Venkatesh Sudhakar K, Fidler Jeff L, Fletcher Joel G, Ehman Eric C, Sheedy Shannon P
From the Department of Radiology (L.C.J., S.S.W., P.J.N., C.F., S.K.V., J.L.F., J.G.F., E.C.E., S.P.S.), Department of Surgery, Division of Hepatobiliary and Pancreas Surgery (T.E.G.), and Department of Laboratory Medicine and Pathology (R.P.G.), Mayo Clinic, 200 1st St SW, Rochester, MN 55905.
Radiographics. 2025 Jun;45(6):e240131. doi: 10.1148/rg.240131.
Pseudomyxoma peritonei involves the gradual accumulation of gelatinous peritoneal metastases, typically resulting from the rupture of a mucinous appendiceal neoplasm. Standard treatment often includes cytoreductive surgery and hyperthermic intraperitoneal chemotherapy. However, recurrence is common despite optimal cytoreduction, prompting ongoing investigation into novel therapies. This comprehensive review aims to enhance radiologists' understanding of mucinous appendiceal neoplasms and pseudomyxoma peritonei by focusing on nomenclature, pathophysiology, optimal imaging strategies, and the typical imaging appearance of mucinous appendiceal neoplasm and associated peritoneal disease. It also highlights problematic areas of disease that may affect the ability to achieve complete cytoreduction or influence surgical decision making and includes a surgeon's perspective on treating this complex condition.
腹膜假黏液瘤表现为胶冻样腹膜转移瘤逐渐积聚，通常由黏液性阑尾肿瘤破裂引起。标准治疗通常包括减瘤手术和腹腔内热灌注化疗。然而，尽管进行了最佳的减瘤手术，复发仍很常见，这促使人们不断探索新的治疗方法。这篇综述旨在通过关注命名、病理生理学、最佳成像策略以及黏液性阑尾肿瘤和相关腹膜疾病的典型影像学表现，提高放射科医生对黏液性阑尾肿瘤和腹膜假黏液瘤的认识。它还强调了可能影响实现完全减瘤或影响手术决策能力的疾病问题领域，并纳入了外科医生对治疗这种复杂疾病的观点。
