Guler Yeliz, Yildirim Abdullah, Uysal Onur K, Genc Omer, Capar Gazi, Halil Ufuk S, Erdogan Aslan, Bozbeyoglu Emrah, Guler Ahmet, Kirma Cevat
Department of Cardiology, Basaksehir Cam and Sakura City Hospital, Istanbul, Turkey.
Department of Cardiology, Adana City Training and Research Hospital, University of Health Sciences, Adana, Turkey.
Heart Lung Circ. 2025 Aug;34(8):821-829. doi: 10.1016/j.hlc.2025.01.005. Epub 2025 May 28.
Contrast-induced acute kidney injury (CI-AKI) is a significant clinical challenge, particularly in patients with ST-segment elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (PCI). This study aimed to evaluate the predictive value of the albumin-bilirubin (ALBI) score for CI-AKI in this high-risk population.
We retrospectively analysed 2,011 patients with STEMI who underwent primary PCI, excluding those with severe renal or liver conditions. CI-AKI occurred in 9.1% of patients. Higher ALBI scores were significantly associated with the development of CI-AKI.
Receiver-operating characteristic analysis revealed that an ALBI score > -2.54 predicted CI-AKI with 70% sensitivity and 61.5% specificity. Logistic regression identified the ALBI score as an independent predictor of CI-AKI (odds ratio 9.731; 95% confidence interval 5.873-16.123; p<0.001).
These findings suggest that the ALBI score, a simple and cost-effective tool, could be integrated into clinical practice to better predict and manage CI-AKI in patients with STEMI undergoing PCI. Further research is warranted to confirm these results and explore the underlying mechanisms.
