Predicting Contrast-Induced Acute Kidney Injury in ST-Segment Elevation Myocardial Infarction Patients Undergoing Percutaneous Coronary Intervention: A Novel Approach.

AIM

Contrast-induced acute kidney injury (CI-AKI) is a significant clinical challenge, particularly in patients with ST-segment elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (PCI). This study aimed to evaluate the predictive value of the albumin-bilirubin (ALBI) score for CI-AKI in this high-risk population.

METHOD

We retrospectively analysed 2,011 patients with STEMI who underwent primary PCI, excluding those with severe renal or liver conditions. CI-AKI occurred in 9.1% of patients. Higher ALBI scores were significantly associated with the development of CI-AKI.

RESULTS

Receiver-operating characteristic analysis revealed that an ALBI score > -2.54 predicted CI-AKI with 70% sensitivity and 61.5% specificity. Logistic regression identified the ALBI score as an independent predictor of CI-AKI (odds ratio 9.731; 95% confidence interval 5.873-16.123; p<0.001).

CONCLUSIONS

These findings suggest that the ALBI score, a simple and cost-effective tool, could be integrated into clinical practice to better predict and manage CI-AKI in patients with STEMI undergoing PCI. Further research is warranted to confirm these results and explore the underlying mechanisms.