• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

最小化小儿肛门直肠畸形修复术后的方差

Minimizing variance in pediatric patients after repair of anorectal malformations.

作者信息

Selesner Leigh, Bigej Ryan, Alturky Sara, Vaughn Cortnie, Gause Colin, Krishnaswami Sanjay, Fialkowski Elizabeth

机构信息

Depart of Surgery, Oregon Health & Science University, Portland, OR, USA.

School of Medicine, Oregon Health & Science University, Portland, OR, USA.

出版信息

Pediatr Surg Int. 2025 May 29;41(1):150. doi: 10.1007/s00383-025-06051-5.

DOI:10.1007/s00383-025-06051-5
PMID:40442369
Abstract

PURPOSE

A standardized anorectal malformation (ARM) perioperative protocol was implemented across two pediatric tertiary hospitals. The protocol addressed antibiotic duration, feeding advancement, VACTERL workup, and wound management. We aim to evaluate complications, length of stay (LOS), and protocol compliance.

METHODS

Introduced in June 2020, data from a 24-month protocol cohort (after a 6-month transition) were compared to a 24-month control cohort. Outcomes included demographics, compliance, complications and LOS.

RESULTS

Forty-five patients were included (control: 26, protocol: 19). Most were diagnosed with rectoperineal fistula (53%), 42% had significant cardiac disease, and 44% underwent prior colostomy. VACTERL workup was completed in 89%. Thirty-five patients underwent posterior sagittal anorectoplasty, and 10 cutback anoplasty. Median postoperative LOS was unchanged (control: 2 days; protocol: 2 days, p=0.80). Total LOS showed no difference (control: 3 days, protocol: 2 days, p = 0.51). No wound infections occurred. Wound dehiscence occurred in 1 control and 2 protocol patients (p=0.57). Compliance was 53% with deviations attributed to early diet initiation (n=4), incomplete VACTERL workup (n=2), and wound care (n=2).

CONCLUSION

A standardized ARM perioperative protocol is feasible across institutions. It maintained excellent outcomes, including short LOS and few complications, though the small sample limited statistical power.

摘要

目的

在两家儿科三级医院实施标准化的肛门直肠畸形(ARM)围手术期方案。该方案涉及抗生素使用时长、喂养进展、VACTERL检查以及伤口处理。我们旨在评估并发症、住院时长(LOS)和方案依从性。

方法

该方案于2020年6月引入,将24个月方案队列(经过6个月过渡期后)的数据与24个月对照队列的数据进行比较。结果包括人口统计学数据、依从性、并发症和住院时长。

结果

共纳入45例患者(对照组:26例,方案组:19例)。大多数患者被诊断为直肠会阴瘘(53%),42%患有严重心脏病,44%曾接受过结肠造口术。89%的患者完成了VACTERL检查。35例患者接受了后矢状位肛门直肠成形术,10例接受了缩减式肛门成形术。术后中位住院时长无变化(对照组:2天;方案组:2天,p = 0.80)。总住院时长无差异(对照组:3天,方案组:2天,p = 0.51)。未发生伤口感染。1例对照组患者和2例方案组患者发生伤口裂开(p = 0.57)。依从性为53%,偏差原因包括过早开始饮食(n = 4)、VACTERL检查不完整(n = 2)以及伤口护理(n = 2)。

结论

标准化的ARM围手术期方案在不同机构间是可行的。尽管样本量小限制了统计效力,但该方案仍保持了良好的结果,包括住院时长短和并发症少。

相似文献

1
Minimizing variance in pediatric patients after repair of anorectal malformations.最小化小儿肛门直肠畸形修复术后的方差
Pediatr Surg Int. 2025 May 29;41(1):150. doi: 10.1007/s00383-025-06051-5.
2
Laparoscopically Assisted Anorectal Pull-Through versus Posterior Sagittal Anorectoplasty for High and Intermediate Anorectal Malformations: A Systematic Review and Meta-Analysis.腹腔镜辅助肛门直肠拖出术与后矢状位肛门直肠成形术治疗中高位肛门直肠畸形的系统评价和Meta分析
PLoS One. 2017 Jan 18;12(1):e0170421. doi: 10.1371/journal.pone.0170421. eCollection 2017.
3
Current practice regarding the diagnosis and treatment of anorectal malformations in female patients: a multicenter questionnaire survey in Japan.日本女性患者肛门直肠畸形诊断与治疗的当前实践:一项多中心问卷调查
Surg Today. 2025 Jul;55(7):960-968. doi: 10.1007/s00595-024-02968-x. Epub 2024 Dec 8.
4
VACTERL Screening in Newborns With Anorectal Malformations - An Opportunity to Optimize Screening Practices, add Gynecologic and Spinal Conditions, and Utilize a New Acronym: VACTE(G)RLS.对患有肛门直肠畸形的新生儿进行VACTERL筛查——优化筛查方法、增加妇科和脊柱疾病筛查以及采用新首字母缩略词VACTE(G)RLS的契机
J Pediatr Surg. 2025 Jun;60(6):162252. doi: 10.1016/j.jpedsurg.2025.162252. Epub 2025 Feb 20.
5
More harm than good? Parental perspectives on dilatations in anorectal malformations.弊大于利?父母对肛门直肠畸形扩张术的看法。
Pediatr Surg Int. 2025 Jun 19;41(1):179. doi: 10.1007/s00383-025-06070-2.
6
Twenty years of experience with Y-V anoplasty for the treatment of minimal rectoperineal fistulas.Y-V成形术治疗轻度直肠会阴瘘20年经验
Pediatr Surg Int. 2025 Jun 19;41(1):181. doi: 10.1007/s00383-025-06092-w.
7
Laparoscopic-assisted anorectal pull-through for anorectal malformations: a systematic review and the need for standardization of outcome reporting.腹腔镜辅助肛门直肠拖出术治疗肛门直肠畸形:系统评价和需要标准化的结局报告。
J Pediatr Surg. 2010 Jul;45(7):1500-4. doi: 10.1016/j.jpedsurg.2009.12.001.
8
Challenges in Transition of Care for Patients With Anorectal Malformations: A Systematic Review and Recommendations for Comprehensive Care.肛门直肠畸形患者过渡期护理的挑战:系统评价和综合护理建议。
Dis Colon Rectum. 2018 Mar;61(3):390-399. doi: 10.1097/DCR.0000000000001033.
9
Early postoperative feeding in single-stage repair of anorectal malformation with vestibular or perineal fistula is not associated with increased wound complications.一期前庭瘘或会阴瘘肛门直肠畸形修复术后早期喂养与增加伤口并发症无关。
J Pediatr Surg. 2023 Mar;58(3):467-470. doi: 10.1016/j.jpedsurg.2022.07.009. Epub 2022 Jul 14.
10
Posterior rectal advancement with fistula preservation in patients with anorectal malformation. A multicenter study.直肠后推移术联合瘘管保留治疗肛门直肠畸形:多中心研究。
Cir Pediatr. 2024 Oct 4;37(4):160-164. doi: 10.54847/cp.2024.04.13.

本文引用的文献

1
Enhanced Recovery After Surgery for Pediatric Abdominal Tumor Resections: A Prospective Multi-institution Study.小儿腹部肿瘤切除术的术后加速康复:一项前瞻性多机构研究。
J Pediatr Surg. 2025 Feb;60(2):162046. doi: 10.1016/j.jpedsurg.2024.162046. Epub 2024 Oct 31.
2
Enhanced Recovery After Surgery Pathways in Pediatric Spinal Surgery: A Systematic Review and Meta-Analysis.加速康复外科路径在小儿脊柱外科中的应用:系统评价和荟萃分析。
World Neurosurg. 2024 Oct;190:329-338. doi: 10.1016/j.wneu.2024.07.170. Epub 2024 Jul 31.
3
Classification and Surgical Management of Anorectal Malformations: A Systematic Review and Evidence-based Guideline From the APSA Outcomes and Evidence-based Practice Committee.
肛门直肠畸形的分类和外科治疗:APSA 结果和循证实践委员会的系统评价和循证指南。
J Pediatr Surg. 2024 Oct;59(10):161598. doi: 10.1016/j.jpedsurg.2024.06.007. Epub 2024 Jun 14.
4
Development of a Standardized Algorithm for Management of Newly Diagnosed Anorectal Malformations.新诊断肛门直肠畸形管理标准化算法的开发
Children (Basel). 2024 Apr 20;11(4):494. doi: 10.3390/children11040494.
5
Evolution of enhanced recovery for children undergoing elective intestinal surgery.儿童择期肠手术中加速康复的演变。
Semin Pediatr Surg. 2024 Apr;33(2):151400. doi: 10.1016/j.sempedsurg.2024.151400. Epub 2024 Mar 28.
6
Protocol for the development of a core outcome set for the optimisation of treatment and follow-up of patients with an anorectal malformation (ARM): The ARM and OUtcome Review (ARMOUR)-project.肛门直肠畸形(ARM)患者治疗和随访优化的核心结局集制定方案:ARM 和结局回顾(ARMOUR)项目。
BMJ Paediatr Open. 2023 Mar;7(1). doi: 10.1136/bmjpo-2022-001691.
7
Screening for VACTERL Anomalies in Children with Anorectal Malformations: Outcomes of a Standardized Approach.筛查肛门直肠畸形患儿的 VACTERL 异常:标准化方法的结果。
J Pediatr Surg. 2023 Jul;58(7):1263-1268. doi: 10.1016/j.jpedsurg.2023.01.051. Epub 2023 Feb 15.
8
Cryoablation in 350 Nuss Procedures: Evolution of Hospital Length of Stay and Opioid Use.350 例 Nuss 手术中的冷冻消融:住院时间和阿片类药物使用的演变。
J Pediatr Surg. 2023 Aug;58(8):1435-1439. doi: 10.1016/j.jpedsurg.2022.10.051. Epub 2022 Nov 7.
9
Standardized perioperative care reduces colorectal surgical site infection in children: A Western Pediatric Surgery Research Consortium multicenter analysis.标准化围手术期护理可降低儿童结直肠手术部位感染:西部儿科外科研究联盟多中心分析
J Pediatr Surg. 2023 Jan;58(1):45-51. doi: 10.1016/j.jpedsurg.2022.09.026. Epub 2022 Sep 26.
10
Implementation of enhanced recovery protocols reduces opioid use in pediatric laparoscopic cholecystectomy surgery.实施强化康复方案可减少小儿腹腔镜胆囊切除术手术中的阿片类药物使用。
Pediatr Surg Int. 2022 Nov;38(11):1517-1523. doi: 10.1007/s00383-022-05195-y. Epub 2022 Aug 11.