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慢性主动脉夹层腔内修复术中的桥接支架:一项范围综述

Bridging stents in endovascular repair of chronic aortic dissection: a scoping review.

作者信息

Jonsdottir Frida R, Resch Timothy A

机构信息

Department of Vascular Surgery, Sjællands University Hospital, Roskilde, Denmark -

Department of Vascular Surgery, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark.

出版信息

J Cardiovasc Surg (Torino). 2025 Jun;66(3):194-202. doi: 10.23736/S0021-9509.25.13383-1. Epub 2025 May 30.

DOI:10.23736/S0021-9509.25.13383-1
PMID:40443284
Abstract

INTRODUCTION

Fenestrated and branched endovascular aortic repair (F/B-EVAR) is increasingly used in the treatment of chronic aortic dissection (cAD), particularly for post-dissection thoracoabdominal aortic aneurysms (PD-TAAA). These aneurysms differ significantly from degenerative aneurysms due to the presence of a true and false lumen, complex target vessel (TV) anatomy, and the higher potential for ongoing aortic remodeling. These factors contribute to technical challenges in target vessel cannulation and raise concerns about the long-term stability of target vessel bridging stents. Although bridging stents play a critical role in achieving durable sealing and target vessel patency, there are currently no clear guidelines for their selection in the setting of PD-TAAA, where anatomical complexity and luminal remodeling pose unique challenges. Bridging stent performance may be influenced by stent design, anatomical configuration, and procedure type, yet evidence specific to this patient population remains limited. This scoping review aims to assess the applicability and outcomes of available bridging stents in the endovascular treatment of PD-TAAA.

EVIDENCE ACQUISITION

This scoping review followed PRISMA-ScR guidelines. A systematic search was conducted in Ovid Medline using keywords related to chronic aortic dissection, bridging stents, FEVAR, and BEVAR. Studies were included if they reported on ≥10 patients with CTBAD treated by FEVAR or BEVAR, with target vessel-specific outcomes. Physician-modified endografts were excluded. Data on patient numbers, stent types, follow-up, and target vessel outcomes (stenosis, occlusion, endoleaks) were extracted.

EVIDENCE SYNTHESIS

Of 50 records screened, three studies met the inclusion criteria, encompassing 375 patients and 1396 treated TVs. All studies were retrospective analyses of prospectively collected data in patients with PD-TAAA. Two studies provided selection criteria for FEVAR vs. BEVAR and specified bridging stent preferences. Fenestrations were typically bridged with balloon-expandable covered stents (BESG), while branches used either BESG or self-expanding covered stents (SESG). Target vessel stenosis or occlusion was more frequently associated with branches, with FEVAR showing superior target vessel patency in one study. No study directly compared BESG and SESG patency. TV-related endoleaks occurred in all studies; two reported no significant difference between FEVAR and BEVAR. Reinterventions were common across all cohorts, primarily due to TV-related complications, with rates approaching 50% at two years.

CONCLUSIONS

In PD-TAAA, the choice between FEVAR, BEVAR, and bridging stent type is largely driven by anatomy and physician preference. The high rate of reinterventions due to target vessel-related complications highlights the need for close postoperative surveillance. Further research is essential to guide optimal bridging stent selection and enhance long-term outcomes.

摘要

引言

开窗和分支型血管腔内主动脉修复术(F/B-EVAR)越来越多地用于治疗慢性主动脉夹层(cAD),特别是用于夹层后胸腹主动脉瘤(PD-TAAA)。由于存在真腔和假腔、复杂的靶血管(TV)解剖结构以及主动脉持续重塑的更高可能性,这些动脉瘤与退行性动脉瘤有显著差异。这些因素导致靶血管插管面临技术挑战,并引发对靶血管桥接支架长期稳定性的担忧。尽管桥接支架在实现持久密封和靶血管通畅方面起着关键作用,但目前在PD-TAAA的情况下,对于其选择尚无明确指南,因为解剖复杂性和管腔重塑带来了独特挑战。桥接支架的性能可能受支架设计、解剖结构和手术类型的影响,但针对该患者群体的具体证据仍然有限。本范围综述旨在评估现有桥接支架在PD-TAAA血管腔内治疗中的适用性和结果。

证据获取

本范围综述遵循PRISMA-ScR指南。在Ovid Medline中使用与慢性主动脉夹层、桥接支架、FEVAR和BEVAR相关的关键词进行了系统检索。如果研究报告了≥10例接受FEVAR或BEVAR治疗的CTBAD患者的靶血管特异性结果,则纳入研究。排除医生改良的腔内移植物。提取了患者数量、支架类型、随访情况和靶血管结果(狭窄、闭塞、内漏)的数据。

证据综合

在筛选的50条记录中,三项研究符合纳入标准,涵盖375例患者和1396条接受治疗的靶血管。所有研究均为对PD-TAAA患者前瞻性收集数据的回顾性分析。两项研究提供了FEVAR与BEVAR的选择标准,并指定了桥接支架偏好。开窗通常用球囊扩张型覆膜支架(BESG)桥接,而分支则使用BESG或自膨式覆膜支架(SESG)。靶血管狭窄或闭塞更常与分支相关,在一项研究中FEVAR显示出更好的靶血管通畅性。没有研究直接比较BESG和SESG的通畅性。所有研究中均发生了与靶血管相关的内漏;两项研究报告FEVAR和BEVAR之间无显著差异。再次干预在所有队列中都很常见,主要是由于与靶血管相关的并发症,两年时发生率接近50%。

结论

在PD-TAAA中选择FEVAR、BEVAR和桥接支架类型在很大程度上取决于解剖结构和医生偏好。由于靶血管相关并发症导致的高再次干预率凸显了术后密切监测的必要性。进一步的研究对于指导最佳桥接支架选择和改善长期结果至关重要。

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