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《肝内胆管癌淋巴结清扫专家共识(2025年版)》

[Expert consensus on lymph node dissection for intrahepatic cholangiocarcinoma(2025)].

出版信息

Zhonghua Wai Ke Za Zhi. 2025 Jul 1;63(7):541-545. doi: 10.3760/cma.j.cn112139-20250421-00213.

DOI:10.3760/cma.j.cn112139-20250421-00213
PMID:40443326
Abstract

Intrahepatic cholangiocarcinoma (ICC) is a highly aggressive malignant tumor with poor prognosis, and lymph node metastasis constitutes one of the critical risk factors contributing to unfavorable patient outcomes. Lymph node dissection holds significant value in accurately staging ICC, guiding prognostic evaluation, and determining adjuvant therapeutic strategies. In recent years, both domestic and international scholars have conducted extensive research on lymph node metastasis and dissection in ICC. However, discrepancies persist among various research findings and consensus guidelines domestically and internationally regarding the understanding and recommendations for lymph node dissection in ICC. Furthermore, substantial variations exist in the extent of lymph node dissection, the minimum number of lymph nodes required for retrieval, and surgical dissection techniques, which have consequently led to divergent research conclusions. To standardize the clinical practice of lymph node dissection for ICC in China and enhance the level of ICC diagnosis and treatment, the Branch of Biliary Surgery, Chinese Society of Surgery, Chinese Medical Association and Working Group of Biliary Surgeons, Chinese College of Surgeons, Chinese Medical Doctor Association, convened relevant experts to develop this expert consensus. This consensus document has been formulated based on the latest evidence-based medical research and accumulated clinical experience.

摘要

肝内胆管癌(ICC)是一种侵袭性很强的恶性肿瘤,预后较差,淋巴结转移是导致患者预后不良的关键危险因素之一。淋巴结清扫在准确分期ICC、指导预后评估及确定辅助治疗策略方面具有重要价值。近年来,国内外学者对ICC的淋巴结转移及清扫进行了广泛研究。然而,国内外不同研究结果及共识指南在ICC淋巴结清扫的理解和推荐方面仍存在差异。此外,淋巴结清扫范围、所需获取的最少淋巴结数量及手术清扫技术也存在很大差异,进而导致研究结论不一。为规范我国ICC淋巴结清扫的临床实践,提高ICC的诊疗水平,中华医学会外科学分会胆道外科学组、中国医师协会外科医师分会胆道外科医师委员会组织相关专家制定了本专家共识。本共识文件基于最新的循证医学研究及积累的临床经验制定。

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