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灯盏乙素揭秘:研究进展与临床治疗前景的深入探索

Eupatilin unveiled: An in-depth exploration of research advancements and clinical therapeutic prospects.

作者信息

Li Zheng, Wang Xiumei, Tasich Ksenija, Hike David, Schumacher Jackson G, Zhou Qingju, Man Weitao, Huang Yong

机构信息

School of Traditional Chinese Medicine, Southern Medical University, Guangzhou, Guangdong Province, China.

Department of Neurosurgery, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Beijing, China.

出版信息

J Transl Int Med. 2025 Apr 24;13(2):104-117. doi: 10.1515/jtim-2025-0016. eCollection 2025 Apr.

Abstract

Eupatilin, a flavonoid found in Artemisia argyi (Compositae) leaves, exhibits robust anti-inflammatory, antioxidant, and anti-tumor properties. Numerous investigations have demonstrated remarkable efficacy of eupatilin across various disease models, spanning digestive, respiratory, nervous, and dermatological conditions. This review aims to provide an overview of recent studies elucidating the mechanistic actions of eupatilin across a spectrum of disease models and evaluate its clinical applicability. The findings herein provide valuable insights for advancing the study of novel Traditional Chinese Medicine compounds and their clinical utilization.

摘要

紫花牡荆素是一种存在于艾叶(菊科)中的黄酮类化合物,具有强大的抗炎、抗氧化和抗肿瘤特性。大量研究表明,紫花牡荆素在各种疾病模型中均显示出显著疗效,涵盖消化、呼吸、神经和皮肤疾病等领域。本综述旨在概述近期关于阐明紫花牡荆素在一系列疾病模型中的作用机制的研究,并评估其临床适用性。本文的研究结果为推进新型中药化合物的研究及其临床应用提供了有价值的见解。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5f30/12116271/8ab8ee5a31f0/j_jtim-2025-0016_fig_001.jpg

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