Mansouri Parvin, Mozafari Nikoo
Medical Laser Research Centers, Academic Center of Education, Culture and Research Tehran University of Medical Sciences Tehran Iran.
Skin Research Center Shahid Beheshti University of Medical Sciences Tehran Iran.
Clin Case Rep. 2025 May 28;13(6):e70536. doi: 10.1002/ccr3.70536. eCollection 2025 Jun.
We present a woman with severe refractory livedoid vasculopathy who was successfully treated with tofacitinib (5 mg twice a day). The ulcers gradually healed over a period of 2-3 months without experiencing any adverse events over a 1-year follow-up period. Tofacitinib may be considered a safe and effective therapy for patients with livedoid vasculopathy.
我们报告了一名患有严重难治性类脂质渐进性坏死性血管病的女性患者,该患者接受托法替布(每日两次,每次5毫克)治疗后获得成功。溃疡在2至3个月内逐渐愈合,在1年的随访期内未出现任何不良事件。对于类脂质渐进性坏死性血管病患者,托法替布可被视为一种安全有效的治疗方法。