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乌干达农村地区接受美因茨II型贮尿囊尿流改道术患者的临床、超声及生化特征。病例系列研究

Clinical, Sonographic and Biochemical Profiles of Patients with a Mainz II Pouch Urine Diversion in Rural Uganda. A Case Series.

作者信息

Kirya Fred, Aderu David, Epodoi Joseph, Apolot Denise, Kiconco Ritah, Mpango Richard, Eperu Jacob, Opito Ronald

机构信息

Department of Surgery, School of Health Sciences, Soroti University, Soroti, Uganda.

Department of Anatomy, School of Health Sciences, Soroti University, Soroti, Uganda.

出版信息

Int Med Case Rep J. 2025 May 24;18:601-607. doi: 10.2147/IMCRJ.S515145. eCollection 2025.

Abstract

BACKGROUND

Mainz II pouch urinary diversion is an alternative surgery for patients with an incurable vesicovaginal fistula (VVF). We report six (6) cases of patients who had incurable VVF and were offered Mainz II pouch surgery at Soroti Regional Referral Hospital, between 2009 and 2018 and followed up in 2023.

METHODS

A retrospective review of charts of 6 patients who were offered Mainz II pouch procedure and a cross-sectional assessment of their biochemical, sonographic and clinical profiles five (5) or more years after the procedure at Soroti Regional Referral Hospital were done. All case notes of patients who underwent the Mainz II procedure between 2009 and 2018 were retrieved from the registry and each patient profiled using a standard data abstraction tool.

RESULTS

The ages of the six participants ranged between 16 and 65 years at the time of the procedure. Four of the 6 participants had lived with the fistula for less than 10 years. Four participants had only one delivery and the other 2 had five and six deliveries. All the participants had lived with the Mainz II pouch urine diversion for at least five years (5-14 years). One participant (1/6) had hypertension (BP=161/101). Most participants reported nocturnal incontinence. Sonographic findings revealed one-sided mild vesicoureteral reflux with loss of corticomedullary differentiation in two participants (2/6). One of six (1/6) patients had severe vesicoureteral reflux grade 4. The commonest metabolic disorders were compensated metabolic acidosis (4/6).

CONCLUSION

The Mainz II pouch procedure remains a viable option for managing incurable obstetric fistulas. However, the prevalence of metabolic complications, including acidosis and renal impairment, underscores the need for routine biochemical and sonographic monitoring to ensure optimal long-term patient outcomes.

摘要

背景

美因茨II型袋式尿流改道术是治疗无法治愈的膀胱阴道瘘(VVF)患者的一种替代手术。我们报告了2009年至2018年间在索罗蒂地区转诊医院接受美因茨II型袋式手术且无法治愈的VVF患者6例,并于2023年进行了随访。

方法

对6例接受美因茨II型袋式手术患者的病历进行回顾性分析,并在索罗蒂地区转诊医院对术后五年或更长时间的患者进行生化、超声和临床特征的横断面评估。从登记处检索2009年至2018年间接受美因茨手术患者的所有病历,并使用标准数据提取工具对每位患者进行分析。

结果

6名参与者在手术时年龄在16至65岁之间。6名参与者中有4名瘘管存在时间不到10年。4名参与者仅分娩1次,另外2名分别分娩5次和6次。所有参与者接受美因茨II型袋式尿流改道术至少5年(5至14年)。1名参与者(1/6)患有高血压(血压=161/101)。大多数参与者报告有夜间尿失禁。超声检查结果显示,2名参与者(2/6)存在单侧轻度膀胱输尿管反流,伴有肾皮质髓质分界不清。6名患者中有1名(1/6)患有4级严重膀胱输尿管反流。最常见的代谢紊乱是代偿性代谢性酸中毒(4/6)。

结论

美因茨II型袋式手术仍然是治疗无法治愈的产科瘘的可行选择。然而,包括酸中毒和肾功能损害在内的代谢并发症的发生率强调了进行常规生化和超声监测以确保患者长期最佳预后的必要性。

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