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病例报告:颞骨骨内动静脉畸形伴耐药性癫痫发作

Case Report: Intraosseous arteriovenous malformation of the temporal bone presenting with drug-resistant seizures.

作者信息

Sharifi Guive, Paraandavaji Elham, Hajikarimloo Bardia, Meybodi Tohid Emami, Behjati Jina, Nilipour Yalda, Kazemi Mohammad Ali, Mohammadi Esmaeil, Khanbabazadeh Sajjad

机构信息

Department of Neurosurgery, Loghman Hospital, Shahid Beheshti University of Medical Science, Tehran, Iran.

Skull Base Research Center, Loghman Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

出版信息

Front Surg. 2025 May 15;12:1510821. doi: 10.3389/fsurg.2025.1510821. eCollection 2025.

Abstract

Intraosseous arteriovenous malformations (AVMs) are rare conditions characterized by the development of AVMs within bones, leading to a variety of symptoms. Temporal bone AVMs are exceedingly uncommon, as evidenced by the small number of reported instances in the medical literature. A 19-year-old male patient presented with persistent seizures that were unresponsive to pharmacological treatments administered over three years. Imaging revealed a non-enhancing lesion measuring 31 × 22 mm in the right temporal lobe, originating from the middle fossa and the right petrous apex. The patient underwent successful surgical resection of the lesion, with no intraoperative complications or postoperative neurological deficits. Diagnosis of AVM was made after intraoperative pathological investigation. Follow-up examinations showed a complete resolution of the patient's seizures. The management of these lesions is challenging and it requires personalized approaches, which depend on clinical presentation, lesion location, progression, and the patient's overall condition.

摘要

骨内动静脉畸形(AVM)是一种罕见疾病,其特征是在骨骼内形成AVM,可导致多种症状。颞骨AVM极为罕见,医学文献中报道的病例数量很少就证明了这一点。一名19岁男性患者出现持续性癫痫发作,三年来接受药物治疗均无反应。影像学检查显示右侧颞叶有一个31×22毫米的无强化病变,起源于中颅窝和右侧岩尖。患者接受了病变的成功手术切除,术中无并发症,术后无神经功能缺损。术中病理检查后确诊为AVM。随访检查显示患者癫痫发作完全缓解。这些病变的治疗具有挑战性,需要个性化方法,这取决于临床表现、病变位置、进展情况以及患者的整体状况。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1f80/12119634/710d3cf38c06/fsurg-12-1510821-g001.jpg

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