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Immune Checkpoint Inhibitors: Think Beyond Cardiotoxicity! Is Physical Deconditioning a New Marker of Disease?

作者信息

Almeida Roberto de Castro Meirelles de, Castro Issa Aurora Felice, Santos Felix Alex Dos

机构信息

Echocardiography Laboratory, National Institute of Cardiology, Rio de Janeiro, Brazil.

National Institute of Cardiology, Rio de Janeiro, Brazil.

出版信息

Echocardiography. 2025 Jun;42(6):e70179. doi: 10.1111/echo.70179.

DOI:10.1111/echo.70179
PMID:40444414
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12123556/
Abstract
摘要

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Longitudinal Evaluation of Immune Checkpoint Inhibitor-Induced Fatigue Syndrome by Rest, Stress, and Speckle-Tracking Strain Echocardiography.通过休息、应激和斑点追踪应变超声心动图对免疫检查点抑制剂诱发疲劳综合征的纵向评估
Echocardiography. 2025 Apr;42(4):e70158. doi: 10.1111/echo.70158.
2
Effects of Systemic Anticancer Treatment on Cardiorespiratory Fitness: A Systematic Review and Meta-Analysis.全身抗癌治疗对心肺适能的影响：一项系统评价与荟萃分析
JACC CardioOncol. 2025 Feb;7(2):96-106. doi: 10.1016/j.jaccao.2024.11.004. Epub 2025 Jan 14.
3
Cardiovascular toxicities of immune therapies for cancer - a scientific statement of the Heart Failure Association (HFA) of the ESC and the ESC Council of Cardio-Oncology.癌症免疫治疗的心血管毒性——欧洲心脏病学会心力衰竭协会（HFA）和欧洲心脏病学会心血管肿瘤学理事会的科学声明。
Eur J Heart Fail. 2024 Oct;26(10):2055-2076. doi: 10.1002/ejhf.3340. Epub 2024 Aug 1.
4
Immune Checkpoint Inhibitor Therapy in Oncology: Current Uses and Future Directions: State-of-the-Art Review.肿瘤学中的免疫检查点抑制剂疗法：当前应用与未来方向：最新综述
JACC CardioOncol. 2022 Dec 20;4(5):579-597. doi: 10.1016/j.jaccao.2022.09.004. eCollection 2022 Dec.
5
2022 ESC Guidelines on cardio-oncology developed in collaboration with the European Hematology Association (EHA), the European Society for Therapeutic Radiology and Oncology (ESTRO) and the International Cardio-Oncology Society (IC-OS).2022年欧洲心脏病学会（ESC）与欧洲血液学协会（EHA）、欧洲治疗放射学与肿瘤学协会（ESTRO）以及国际心脏肿瘤学会（IC-OS）合作制定的心脏肿瘤学指南。
Eur Heart J. 2022 Nov 1;43(41):4229-4361. doi: 10.1093/eurheartj/ehac244.
6
Physical Activity in Cancer Prevention and Survival: A Systematic Review.体力活动在癌症预防和生存中的作用：系统评价。
Med Sci Sports Exerc. 2019 Jun;51(6):1252-1261. doi: 10.1249/MSS.0000000000001937.
7
The Next Immune-Checkpoint Inhibitors: PD-1/PD-L1 Blockade in Melanoma.下一代免疫检查点抑制剂：黑色素瘤中的PD-1/PD-L1阻断
Clin Ther. 2015 Apr 1;37(4):764-82. doi: 10.1016/j.clinthera.2015.02.018. Epub 2015 Mar 29.