Suppr超能文献

使用限制性髁型膝关节假体的翻修全膝关节置换术的生存率及并发症:一项至少10年的随访研究

Survivorship and Complications in Revision Total Knee Arthroplasty With a Constrained Condylar Knee Implant: A Minimum 10-Year Follow-Up Study.

作者信息

Greenberg Arieh, Braunstein Doris, Abughaduma Nada R, Gross Allen, Safir Oleg, Kuzyk Paul, Wolfstadt Jesse, Backstein David

机构信息

Granovsky Gluskin Orthopedic Division, Sinai Health System, University of Toronto, Toronto, Canada.

出版信息

J Arthroplasty. 2025 May 28. doi: 10.1016/j.arth.2025.05.088.

Abstract

BACKGROUND

Constrained condylar knee (CCK) prostheses are commonly utilized in revision total knee arthroplasty (rTKA) when additional constraint is needed due to ligamentous insufficiency. However, data on long-term outcomes remain limited. This study evaluated the survivorship and complications of CCK implants over a minimum 10-year follow-up, extending up to 23 years.

METHODS

We retrospectively analyzed 345 rTKA procedures with CCK implants performed between 2001 and 2014. The cohort included 190 women (55%) and 155 men (45%), with a mean age of 69 years (range, 36 to 92). The mean follow-up duration was 13.5 years (range, 10 to 23.3 years). The primary indication for initial TKA was osteoarthritis (81%). Revisions were performed for aseptic loosening (23.2%), infection (22.9%), malrotation/malalignment (14.2%), and instability (13%). Femoral augments were used in 238 cases, tibial augments in 62 cases, and void fillers for bone defects in 25 patients. Kaplan-Meier survival analysis assessed implant longevity, defining failure as revision for any cause and revision due to aseptic loosening.

RESULTS

Kaplan-Meier analysis demonstrated favorable long-term implant survivorship. All-cause revision-free survival was 95.1% (95% CI [confidence interval]: 92.7 to 97.5) at 5 years and 93.6% (95% CI: 91.0 to 96.2) from 10 years onward. Survival free from aseptic loosening was 98.5% (95% CI: 97.1 to 99.9) at 5 years and 97.9% (95% CI: 96.3 to 99.5) through 20 years. The number of knees at risk declined over time, from 314 at 10 years to 16 at 20 years. A total of 25 complications occurred at a mean of 2.9 years post-revision, with 22 requiring surgical intervention. The leading causes for re-revision were infection (54.5%) and aseptic loosening (31.8%).

CONCLUSIONS

The CCK implants demonstrate favorable long-term survivorship in rTKA at a minimum 10-year follow-up. These findings support the continued use of CCK implants in rTKA with appropriate patient selection and careful surgical technique.

摘要

背景

当因韧带功能不全需要额外的约束时,受限髁膝关节(CCK)假体常用于翻修全膝关节置换术(rTKA)。然而,关于长期疗效的数据仍然有限。本研究评估了CCK植入物在至少10年随访期(最长达23年)内的生存率和并发症情况。

方法

我们回顾性分析了2001年至2014年间进行的345例采用CCK植入物的rTKA手术。该队列包括190名女性(55%)和155名男性(45%),平均年龄69岁(范围36至92岁)。平均随访时间为13.5年(范围10至23.3年)。初次全膝关节置换术的主要指征是骨关节炎(81%)。翻修的原因包括无菌性松动(23.2%)、感染(22.9%)、旋转不良/对线不良(14.2%)和不稳定(13%)。238例使用了股骨增强物,62例使用了胫骨增强物,25例患者使用了骨缺损填充剂。采用Kaplan-Meier生存分析评估植入物的使用寿命,将任何原因导致的翻修以及无菌性松动导致的翻修定义为失败。

结果

Kaplan-Meier分析显示植入物具有良好的长期生存率。5年时无任何原因的翻修生存率为95.1%(95%置信区间[CI]:92.7至97.5),10年及以后为93.6%(95%CI:91.0至96.2)。5年时无无菌性松动的生存率为98.5%(95%CI:97.1至99.9),20年时为97.9%(95%CI:96.3至99.5)。处于风险中的膝关节数量随时间减少,从10年时的314例降至20年时的16例。总共发生了25例并发症,平均发生在翻修后2.9年,其中22例需要手术干预。再次翻修的主要原因是感染(54.5%)和无菌性松动(31.8%)结论:在至少10年的随访中,CCK植入物在rTKA中显示出良好的长期生存率。这些发现支持在合适的患者选择和谨慎的手术技术下,继续在rTKA中使用CCK植入物。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验