超声引导下平阳霉素硬化治疗眶周淋巴管畸形
Ultrasound-guided sclerotherapy of pingyangmycin for periorbital lymphatic malformations.
作者信息
Li Yixiao, Wang Liang, Song Dan, Jiao Bingxuan, Li Jing, Zhou Jie, Guo Lei
机构信息
Department of Cheeloo College of Medicine, Shandong University, Jinan, 250001, China.
Department of Vascular Anomalies and Interventional Radiology, Children's Hospital Affiliated to Shandong University, Jinan, China.
出版信息
BMC Ophthalmol. 2025 May 30;25(1):319. doi: 10.1186/s12886-025-04154-0.
BACKGROUND
This study investigated the treatment outcomes of ultrasound-guided sclerotherapy with pingyangmycin for periorbital lymphatic malformations (LMs).
METHOD
A retrospective study of patients with periorbital LMs who underwent ultrasound-guided sclerotherapy in our department between 2017 and 2024 was conducted.
RESULTS
One boy and seven girls with periorbital LMs were analyzed. Four cases had intraorbital lesions, two cases had lesions of the eyelids, and two cases had mixed lesions. Eight children underwent 13 sclerotherapy sessions, fluid was able to be withdrawn with a median amount of aspirate of 2 ml. After treatment, one of the eight children was lesion not seen on imaging, six showed strong improvement, and one showed weak improvement. None of the children experienced procedure-related adverse reactions.
CONCLUSIONS
Ultrasound-guided sclerotherapy is a treatment modality for periorbital LMs with good efficacy and few potential risks.
背景
本研究探讨了超声引导下平阳霉素硬化治疗眼眶周围淋巴管畸形（LMs）的治疗效果。
方法
对2017年至2024年在我科接受超声引导下硬化治疗的眼眶周围LMs患者进行回顾性研究。
结果
分析了1例男孩和7例女孩眼眶周围LMs患者。4例有眶内病变，2例有眼睑病变，2例有混合病变。8名儿童接受了13次硬化治疗，中位抽吸出液体量为2ml。治疗后，8名儿童中有1名影像学上未见病变，6名改善明显，1名改善不明显。所有儿童均未出现与治疗相关的不良反应。
结论
超声引导下硬化治疗是一种治疗眼眶周围LMs的方法，疗效良好且潜在风险少。
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