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缺铁性贫血患者舌上皮萎缩性变化的形态计量分析

Morphometric analysis of atrophic changes in human lingual epithelium in iron deficiency anaemia.

作者信息

Scott J, Valentine J A, St Hill C A, West C R

出版信息

J Clin Pathol. 1985 Sep;38(9):1025-9. doi: 10.1136/jcp.38.9.1025.

Abstract

A stereological analysis of epithelial structure at the lateral surface of the tongue showed that iron deficiency anaemia was associated with reduced epithelial thickness despite the absence of overt mucosal abnormalities. The epithelial atrophy was entirely due to a reduction in the size and number of cells in the maturation compartment. By contrast, the progenitor cell compartment was increased in thickness due to an increase in the number of cells. This hyperplastic reaction may be a trophic response to the overall loss of epithelium in this condition.

摘要

对舌外侧表面上皮结构的体视学分析表明,尽管没有明显的黏膜异常,但缺铁性贫血与上皮厚度降低有关。上皮萎缩完全是由于成熟区细胞大小和数量减少所致。相比之下,祖细胞区因细胞数量增加而厚度增加。这种增生反应可能是对这种情况下上皮整体丧失的一种营养反应。

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本文引用的文献

3
The tongue and oesophagus in iron-deficiency anaemia and the effect of iron therapy.
J Clin Pathol. 1961 Nov;14(6):603-9. doi: 10.1136/jcp.14.6.603.
5
The buccal mucosa in anaemia.贫血时的颊黏膜
J Clin Pathol. 1960 Nov;13(6):463-8. doi: 10.1136/jcp.13.6.463.
7
Quantitative analysis of human buccal epithelium in iron deficiency anaemia.
J Oral Pathol. 1982 Feb;11(1):39-46. doi: 10.1111/j.1600-0714.1982.tb00141.x.
8
Cell kinetics of hamster ventral tongue epithelium in iron deficiency.
Arch Oral Biol. 1984;29(3):195-9. doi: 10.1016/0003-9969(84)90054-2.
9
Oral mucosal changes in iron deficiency anemia in a Sri Lankan female population.
Oral Surg Oral Med Oral Pathol. 1983 Jan;55(1):29-32. doi: 10.1016/0030-4220(83)90302-x.

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