Zhou Jiabao, Lefley Diane, Ottewell Penelope
Division of Clinical Medicine, University of Sheffield, Medical School, Sheffield, UK.
Methods Mol Biol. 2025;2885:399-421. doi: 10.1007/978-1-0716-4306-8_21.
This chapter aims to offer a thorough overview of mouse models used in the study of breast cancer bone metastasis. The primary emphasis is to guide researchers through the procedural steps essential for establishing and utilizing these models within their own studies. These detailed methods are aimed to help researchers acquire reliable, accurate, and meaningful results suitable for publication and subsequent translation into clinical advancements for women affected by breast cancer-induced bone metastasis.
本章旨在全面概述用于乳腺癌骨转移研究的小鼠模型。主要重点是指导研究人员了解在其自身研究中建立和使用这些模型所必需的程序步骤。这些详细方法旨在帮助研究人员获得适用于发表并随后转化为针对受乳腺癌诱导骨转移影响的女性的临床进展的可靠、准确且有意义的结果。