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酸奶与2型糖尿病风险降低:探索美国食品药品监督管理局的合格健康声明及其对改善公众健康的潜在影响

Yogurt and Reduced Risk of Type 2 Diabetes: Exploring the Food and Drug Administration Qualified Health Claim and Potential Implications for Improving Public Health.

作者信息

Freitas Miguel, O'Connor Annalouise, Blechman Amanda, Cifelli Christopher J, Reinhardt Kapsak Wendy

机构信息

Research & Innovation, Danone North America, White Plains, NY, United States.

Research & Innovation, Danone North America, White Plains, NY, United States.

出版信息

J Nutr. 2025 Aug;155(8):2475-2484. doi: 10.1016/j.tjnut.2025.05.027. Epub 2025 May 29.

Abstract

Type 2 diabetes (T2D) is a significant public health burden in the United States today. As the incidence is predicted to increase, advancing our understanding of food-based recommendations that reduce risk of T2D is critical to improve public health. Over the past 2 decades, a body of scientific evidence has emerged demonstrating the association between consumption of dairy yogurt and reduced risk of T2D. This culminated in 2024, with the decision of the United States Food and Drug Administration (FDA) to announce a qualified health claim on the consumption of yogurt and reduced T2D risk. Qualified health claims enable specific messaging on the role that a food may play in mediating disease risk. As yogurt is a component of the underconsumed dairy food group within the Dietary Guidelines for Americans, communication on the relationship between yogurt and T2D risk can help encourage the public to increase intake of yogurt and, with it, nutrients of public health concern such as calcium. The key research included in the FDA enforcement discretion letter and evidence-based review is outlined. This Perspective illustrates the outcome of multisector work that includes scientific researchers, nonprofit and industry partners, and policymakers in the development and activation of science-based public health messaging.

摘要

2型糖尿病(T2D)如今是美国一项重大的公共卫生负担。由于预计发病率会上升,加深我们对降低T2D风险的基于食物的建议的理解,对于改善公众健康至关重要。在过去20年里,一系列科学证据表明食用酸奶与降低T2D风险之间存在关联。这在2024年达到高潮,美国食品药品监督管理局(FDA)决定宣布一项关于食用酸奶与降低T2D风险的有条件健康声明。有条件健康声明允许就某种食物在调节疾病风险中可能发挥的作用进行特定宣传。由于酸奶是《美国膳食指南》中摄入不足的乳制品组的一个组成部分,关于酸奶与T2D风险之间关系的宣传有助于鼓励公众增加酸奶的摄入量,进而增加诸如钙等受公众健康关注的营养素的摄入量。概述了FDA执法自由裁量权信函和循证审查中包含的关键研究。本观点阐述了多部门合作的成果,这些部门包括科研人员、非营利组织和行业合作伙伴以及政策制定者,他们共同开展了基于科学的公共卫生宣传的制定和推广工作。

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