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肘关节剥脱性骨软骨炎手术后的翻修率:一项系统评价。

Revision rate after surgery for elbow osteochondritis dissecans: a systemic review.

作者信息

Chen Kuan-Ting, Chou Paul Pei-Hsi, Chiu Po-Chun, Chang Jung-Hsiu

机构信息

Department of General Medicine, Shin Kong Wu Ho-Su Memorial Hospital, Taipei, Taiwan.

Department of Orthopaedic Surgery, Kaohsiung Medical University Hospital, 100 Shih-Chuan First Road, Kaohsiung, 807, Taiwan.

出版信息

J Orthop Surg Res. 2025 May 31;20(1):555. doi: 10.1186/s13018-025-05788-y.

DOI:10.1186/s13018-025-05788-y
PMID:40450334
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12126901/
Abstract

BACKGROUND

Humeral capitellum osteochondritis dissecans (OCD) is a common condition among overhead throwing athletes and is typically treated surgically. While stable lesions can be treated nonoperatively, untreated unstable lesions can lead to significant elbow discomfort and impaired quality of life. This study reviews the revision rate and interval in athletes with elbow OCD following primary surgery.

METHODS

Data was extracted from PubMed, Embase, and Medline between 1990 and 2022, and two reviewers independently screened the duplicate reports of complications and revision surgeries. The Methodological Index for Nonrandomized Research score was used for risk of bias assessment. Inclusion criteria were as follows: studies in the English language, those involving humans, those reporting complications, and those performing revision surgeries following capitellar OCD surgery. Logit transformation and random effects were calculated using the Der Simonian Laired estimator, and the Shapiro-Wilk test was first performed to determine whether revision interval data followed a normal distribution. The Wilcoxon rank sum test was used for nonparametric data comparison, while Spearman's rank correlation assessed whether shorter follow-up periods underestimated the revision rate.

RESULTS

A total of 6,457 studies were identified through the initial literature search (PubMed: 1,924; Embase: 2,532; Medline: 2,001), with 4,147 duplicates removed, leaving 2,310 unique studies for screening. After applying the inclusion criteria, 20 full-text articles were selected, all of which were level IV case series with MINORS scores ranging from 7 to 14 (mean: 10.65), demonstrating moderate heterogeneity (I = 41%) and strong inter-reviewer agreement across screening phases (κ = 0.78-0.98). Twenty studies involving 477 elbows (474 athletes) were included, 55 of which underwent revision surgery. The athletes were divided into debridement, microfracture, and osteochondral grafting groups. The overall revision rate was 11.53%, and the revision rate of the three groups were 11.2%, 14.2%, and 9.19%, respectively. Eleven of the 20 studies (24 of 175 athletes underwent revision surgery) with complete data were included in interval analysis of revision surgery. The mean intervals of all participants and three groups were 25, 41.8, 10.4, and 24.2 months, respectively. Spearman's rank correlation showed no significant association between the follow-up duration and the revision rate (rho = -0.31, p = 0.18) or the revision interval (rho = 0.02, p = 0.95) in the overall cohort. Correlation coefficients across surgical subgroups also varied in direction and were not statistically significant.

CONCLUSION

Approximately 11% of patients required revision surgery following primary treatment for elbow OCD, with an average interval of 25 months. No significant association between follow-up duration and either revision rate or revision interval. Thus, further investigations, rehabilitation programs may be required to decrease this revision rate.

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/60bc/12126901/42d9f73e1dcd/13018_2025_5788_Fig3a_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/60bc/12126901/02f32effe94f/13018_2025_5788_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/60bc/12126901/139c1f581b58/13018_2025_5788_Fig2a_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/60bc/12126901/42d9f73e1dcd/13018_2025_5788_Fig3a_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/60bc/12126901/02f32effe94f/13018_2025_5788_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/60bc/12126901/139c1f581b58/13018_2025_5788_Fig2a_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/60bc/12126901/42d9f73e1dcd/13018_2025_5788_Fig3a_HTML.jpg
摘要

背景

肱骨小头剥脱性骨软骨炎(OCD)在过头投掷运动员中很常见,通常采用手术治疗。虽然稳定的损伤可以非手术治疗,但未经治疗的不稳定损伤会导致严重的肘部不适和生活质量下降。本研究回顾了初次手术后肘部OCD运动员的翻修率和时间间隔。

方法

从1990年至2022年期间的PubMed、Embase和Medline中提取数据,两名评审员独立筛选并发症和翻修手术的重复报告。使用非随机研究方法学指数评分进行偏倚风险评估。纳入标准如下:英文研究、涉及人类的研究、报告并发症的研究以及在肱骨小头OCD手术后进行翻修手术的研究。使用Der Simonian Laired估计器计算对数转换和随机效应,首先进行Shapiro-Wilk检验以确定翻修间隔数据是否呈正态分布。Wilcoxon秩和检验用于非参数数据比较,而Spearman秩相关评估较短的随访期是否低估了翻修率。

结果

通过初步文献检索共识别出6457项研究(PubMed:1924项;Embase:2532项;Medline:2001项),去除4147项重复研究后,留下2310项独特研究进行筛选。应用纳入标准后,选择了20篇全文文章,所有文章均为IV级病例系列,MINORS评分范围为7至14(平均:10.65),显示出中度异质性(I² = 41%),且在筛选阶段评审员之间具有较强的一致性(κ = 0.78 - 0.98)。纳入了涉及477个肘部(474名运动员)的20项研究,其中55个接受了翻修手术。运动员被分为清创、微骨折和骨软骨移植组。总体翻修率为11.53%,三组的翻修率分别为11.2%、14.2%和9.19%。20项研究中有11项(175名运动员中的24名接受了翻修手术)具有完整数据,纳入翻修手术的时间间隔分析。所有参与者和三组的平均时间间隔分别为25、41.8、10.4和24.2个月。Spearman秩相关显示,在整个队列中,随访时间与翻修率(rho = -0.31,p = 0.18)或翻修间隔(rho = 0.02,p = 0.95)之间无显著关联。手术亚组间的相关系数在方向上也有所不同,且无统计学意义。

结论

约11%的患者在肘部OCD初次治疗后需要翻修手术,平均间隔为25个月。随访时间与翻修率或翻修间隔之间无显著关联。因此,可能需要进一步研究和康复计划以降低该翻修率。

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本文引用的文献

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Osteochondritis dissecans of the knee: Epidemiology, etiology, and natural history.膝关节剥离性骨软骨炎:流行病学、病因及自然病史
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Both Debridement and Microfracture Produce Excellent Results for Osteochondritis Dissecans Lesions of the Capitellum: A Systematic Review.
清创术和微骨折术治疗肱骨小头剥脱性骨软骨炎病变均产生优异疗效:一项系统评价
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