Yuan R T, Cohen M J
J Hand Surg Am. 1985 Sep;10(5):719-22. doi: 10.1016/s0363-5023(85)80217-3.
Invasive fungal infections of the hand are extremely rare and usually require an immunocompromised host. We report the first known case of Candida albicans tenosynovitis of the hand presenting as a mass in a boy with Buckley's immunodeficiency. Treatment was successful after radical synovectomy of both the flexor and extensor aspects of the hand after he failed to respond to combined amphotericin B and 5-fluorouracil therapy. Fungal tenosynovitis should be considered when swelling and decreased range of motion occur in the hands or digits of an immunocompromised host, especially if pain is not a prominent symptom.
手部侵袭性真菌感染极为罕见,通常发生于免疫功能低下的宿主。我们报告首例已知的白色念珠菌性手部腱鞘炎,表现为一名患有巴克利免疫缺陷的男孩手部出现肿块。在联合使用两性霉素B和5-氟尿嘧啶治疗无效后,对手部屈侧和伸侧进行根治性滑膜切除术后治疗成功。当免疫功能低下的宿主手部或手指出现肿胀和活动范围减小时,尤其是疼痛不突出时,应考虑真菌性腱鞘炎。