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[尿石症的代谢评估。合理的限度是什么?2:实际方法]

[Metabolic evaluation of urinary calculi. What is a reasonable limitation? 2: Practical approach].

作者信息

Jourdan J L, Lanson Y

出版信息

J Urol (Paris). 1985;91(3):175-9.

PMID:4045214
Abstract

There appears to be little justification for conducting major metabolic screening for all cases of urinary calculi, both because of the cost, and the weak therapeutic advantages faced with the increased urine output. It is more logical to use simple methods to distinguish two groups of patients: Those in whom the affection is easily curable: dietary excess, abuse of therapeutic means, hyperparathyroidism, uric acid stones. Those in whom the affection may become worse: cystinuria, urinary malformations, recurrent calculi. Simple investigations in all patients should be: Antecedents, regimens, drugs. Radiography, analysis of stones, allowing for errors. Cystinuria, urinary pH. Creatininemia, uricemia, calcemia. Examinations must be performed effectively, even in outpatients, and the results read (not always the case). For patients at risk, discovered initially or only after this first selection, excretion anomalies are investigated, only a few of them being submitted to a Pak's test.

摘要

对所有尿石症病例进行大规模代谢筛查似乎没有什么正当理由,这既是因为成本问题,也是因为增加尿量所面临的微弱治疗优势。使用简单方法区分两组患者更为合理:一类是病情易于治愈的患者:饮食过量、滥用治疗手段、甲状旁腺功能亢进、尿酸结石。另一类是病情可能恶化的患者:胱氨酸尿症、泌尿系统畸形、复发性结石。所有患者都应进行的简单检查包括:病史、治疗方案、用药情况。X线摄影、结石分析,同时考虑到误差。胱氨酸尿症、尿液pH值。血肌酐、血尿酸、血钙。即使是门诊患者,检查也必须有效进行,并且要解读检查结果(情况并非总是如此)。对于最初发现或仅在首次筛选后发现的高危患者,要调查排泄异常情况,其中只有少数患者要接受帕克试验。

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