Khan Zaraq R, Huffines Rhiannon, Majeed Imad, Hannan Kenneth
Infectious Diseases, University of Louisville Hospital, Louisville, USA.
Internal Medicine, University of Louisville Hospital, Louisville, USA.
Cureus. 2025 May 1;17(5):e83290. doi: 10.7759/cureus.83290. eCollection 2025 May.
Cytomegalovirus (CMV) can cause ulcerative lesions in the gastrointestinal tract, but it does not typically cause severe infections in immunocompetent patients. CMV colitis presenting as a rectal mass is a very rare manifestation often mimicking malignancy. This is an 89-year-old Caucasian female patient with a circumferential ulcerating mass and a sigmoid polyp that was found to be positive for CMV in the immunohistochemical staining. This is a rare presentation of CMV colitis, especially in an immunocompetent patient. The rarity of this disease presentation exemplifies the importance of a thorough workup for diagnosis.
巨细胞病毒（CMV）可导致胃肠道出现溃疡性病变，但在免疫功能正常的患者中通常不会引起严重感染。表现为直肠肿物的CMV结肠炎是一种非常罕见的表现，常酷似恶性肿瘤。这是一名89岁的白种女性患者，有一个环形溃疡性肿物和一个乙状结肠息肉，免疫组化染色发现其CMV呈阳性。这是CMV结肠炎的一种罕见表现，尤其是在免疫功能正常的患者中。这种疾病表现的罕见性体现了进行全面检查以明确诊断的重要性。
