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一期原发性腭裂修复与植骨:单侧唇腭裂与单侧唇腭裂牙槽突裂的比较。

Single-Stage Primary Palatal Closure and Bone Grafting: A Comparison Between Unilateral Cleft Lip and Alveolus and Unilateral Cleft Lip and Palate.

作者信息

Imura Hideto, Niimi Teruyuki, Yoshida Maya, Sakuma Chisato, Ito Masaaki, Akiyama Yasunori, Kitagawa Ken, Natsume Nagana, Furukawa Hiroo, Natsume Nagato

机构信息

Cleft Lip and Palate Center, Aichi Gakuin University, Nagoya, JPN.

Division of Research and Treatment for Oral and Maxillofacial Congenital Anomalies, School of Dentistry, Aichi Gakuin University, Nagoya, JPN.

出版信息

Cureus. 2025 May 2;17(5):e83347. doi: 10.7759/cureus.83347. eCollection 2025 May.

Abstract

Background This study aimed to evaluate the outcomes of secondary alveolar bone grafting by assessing grafted bone resorption in the alveolar region and the anterior third of the hard palate in patients with unilateral cleft lip and palate (UCLP). A modified protocol involving simultaneous alveoloplasty and anterior palate closure was employed to optimize surgical outcomes and reduce the number of required procedures. Materials and methods A total of 55 patients were retrospectively evaluated: 16 with unilateral cleft lip and alveolus (UCLA) who underwent bone grafting limited to the alveolar cleft and 39 with UCLP who received simultaneous alveolar bone grafting and closure of the anterior one-third of the hard palate. All patients underwent surgery between 2012 and 2019. Surgical outcomes were assessed using the 6-point Standardized Way to Assess Grafts (SWAG) scale, based on postoperative dental radiographs. Bone fill was independently evaluated at the coronal, middle, and apical thirds of the cleft site. Results The median ages at surgery were 10.5 years (range: 8.75-12.6) for the UCLA group and 10.59 years (range: 8.33-15.3) for the UCLP group, with no significant age difference between groups. The mean total SWAG scores indicated favorable bone graft outcomes in both. Notably, complete bone fill (score 2) in the apical third was observed in all patients. No significant difference was found in bone resorption patterns between groups, and no resorption was noted on the apical side in either group. The difference in bone level at each third (coronal, middle, apical) between groups was not statistically significant. These findings highlight the efficacy of simultaneous anterior palate closure in reducing graft resorption and enhancing bone stability. Conclusions Simultaneous alveolar bone grafting and anterior hard palate closure in patients with UCLP is a clinically effective treatment protocol. It achieves stable bone regeneration with minimal resorption, reduces the need for multiple procedures, and enables reliable assessment through routine clinical radiographs. The SWAG scale proved to be a practical and reproducible tool for postoperative evaluation, and these findings provide valuable baseline data for clinical decision-making and informed consent.

摘要

背景 本研究旨在通过评估单侧唇腭裂(UCLP)患者牙槽区域和硬腭前三分之一处移植骨的吸收情况,来评价二期牙槽骨植骨的效果。采用了一种改良方案,即同时进行牙槽成形术和前腭部闭合术,以优化手术效果并减少所需手术的次数。

材料与方法 对55例患者进行回顾性评估:16例单侧唇裂合并牙槽突裂(UCLA)患者仅接受牙槽裂植骨,39例UCLP患者同时接受牙槽骨植骨和硬腭前三分之一的闭合术。所有患者均在2012年至2019年期间接受手术。基于术后牙科X线片,采用6分标准化移植物评估方法(SWAG)量表评估手术效果。在裂隙部位的冠部、中部和根尖部三分之一处独立评估骨填充情况。

结果 UCLA组手术时的中位年龄为10.5岁(范围:8.75 - 12.6岁),UCLP组为10.59岁(范围:8.33 - 15.3岁),两组之间年龄无显著差异。平均总SWAG评分表明两组的骨移植效果均良好。值得注意的是,所有患者根尖部三分之一处均观察到完全骨填充(评分为2分)。两组之间的骨吸收模式无显著差异,两组的根尖侧均未观察到吸收。两组在每个三分之一处(冠部、中部、根尖部)的骨水平差异无统计学意义。这些发现突出了同时进行前腭部闭合术在减少移植骨吸收和增强骨稳定性方面的有效性。

结论 对于UCLP患者,同时进行牙槽骨植骨和前硬腭闭合术是一种临床有效的治疗方案。它能实现稳定的骨再生,吸收极少,减少了多次手术的需求,并能通过常规临床X线片进行可靠评估。SWAG量表被证明是一种实用且可重复的术后评估工具,这些发现为临床决策和知情同意提供了有价值的基线数据。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df96/12126962/fc59cb383928/cureus-0017-00000083347-i01.jpg

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