Desai Binoy, Singh Harjit, Martorella Alessandra, Kunkle Bryce, Rangnekar Amol S
Mount Sinai Health System, New York, New York, USA.
MedStar Georgetown University Hospital, Washington, District of Columbia, USA.
Case Reports Hepatol. 2025 May 24;2025:9961539. doi: 10.1155/crhe/9961539. eCollection 2025.
Hepatic amyloidosis is a rare condition that leads to progressive liver dysfunction. Diagnosis is often challenging since clinical presentation may be highly varied and is dependent upon the extent of liver involvement, underlying etiology of amyloid deposition, as well as concomitant extrahepatic manifestations. Ascites, although uncommon, can be a presenting feature of hepatic amyloidosis and pose diagnostic challenges as it can occur in a variety of liver and nonliver-related conditions. Herein, we present a case of hepatic amyloidosis in a patient with recurrent ascites, emphasizing the importance of considering this condition in the differential diagnosis of individuals presenting with unexplained ascites.
肝淀粉样变性是一种罕见的疾病,可导致进行性肝功能障碍。诊断往往具有挑战性,因为临床表现可能高度多样,并且取决于肝脏受累的程度、淀粉样蛋白沉积的潜在病因以及伴随的肝外表现。腹水虽然不常见,但可能是肝淀粉样变性的一个表现特征,并且由于它可发生于多种肝脏及非肝脏相关疾病中,因此会带来诊断上的挑战。在此,我们报告一例复发性腹水患者的肝淀粉样变性病例,强调在不明原因腹水患者的鉴别诊断中考虑这种疾病的重要性。