Xiong Siwei, Peng Maoqin, Zhao Wei, Ren Junru, Yao Dezhong, Qin Yun, Liu Tiejun
The Clinical Hospital of Chengdu Brain Science Institute, MOE Key Lab for Neuroinformation, School of Life Science and Technology, University of Electronic Science and Technology of China, PR China.
Sichuan Institute for Brain Science and Brain-Inspired Intelligence, Chengdu, 611731, PR China.
Int J Clin Health Psychol. 2025 Apr-Jun;25(2):100571. doi: 10.1016/j.ijchp.2025.100571. Epub 2025 May 2.
Cardiac interoception exhibits tight coupling with brain activity, deeply engaging in emotional behavior. However, the neural mechanisms underlying how heart activity influences brain emotional processing remain poorly understood. This study introduced the heartbeat oscillatory potential (HOP), a novel EEG-based index time-locked to ∼0.1 Hz heartbeat oscillations, and examined the change of HOP during 0.1 Hz slow-paced breathing (SPB). Resting-state data from 108 healthy adults revealed that HOP was involved in the frontal and parietal cortices. Data collected from 37 subjects showed that SPB increased HOP in a spatial- and phase-dependent manner, with increased HOP in the right prefrontal cortex around the peak of the ∼0.1 Hz heartbeat oscillations, mediated the association between the heartbeat oscillations and enhanced emotional control. These findings underscore the pivotal role of the right prefrontal cortex in linking cardiac interoception, providing insights into the benefits of SPB on emotional control from a heart-brain interaction perspective.
心脏内感受与大脑活动表现出紧密的耦合，深度参与情绪行为。然而，心脏活动如何影响大脑情绪处理的神经机制仍知之甚少。本研究引入了心跳振荡电位（HOP），这是一种基于脑电图的新型指标，与约0.1Hz的心跳振荡锁时，并研究了0.1Hz慢节奏呼吸（SPB）期间HOP的变化。来自108名健康成年人的静息状态数据显示，HOP涉及额叶和顶叶皮质。从37名受试者收集的数据表明，SPB以空间和相位依赖的方式增加HOP，在约0.1Hz心跳振荡峰值周围的右侧前额叶皮质中HOP增加，介导了心跳振荡与增强的情绪控制之间的关联。这些发现强调了右侧前额叶皮质在连接心脏内感受中的关键作用，从心脑相互作用的角度为SPB对情绪控制的益处提供了见解。
