Lam Hui Yuan, Binti Mohd Zainal Hamidah, Koh Khai Luen, Bin Mat Zain Mohammad Ali
Department of Plastic Reconstructive Surgery, Hospital Kuala Lumpur, 50586, Kuala Lumpur, Malaysia.
Science and Reconstructive Unit, School of Medical Science, Hospital Universiti Sains Malaysia, Kelantan, 16150, Malaysia.
World J Plast Surg. 2025;14(1):93-97. doi: 10.61186/wjps.14.1.93.
Necrotising fasciitis (NF) is a rare, severe, rapidly progressive, and life-threatening synergistic infection that primarily affects the superficial fascia. Although unusual in head and neck surgeries, necrotizing fasciitis may have drastic consequences. Dental problems, burns, trauma, and peritonsillar abscesses often cause the condition. We describe a rare case of extensive facial necrotising fasciitis secondary to carbimazole-induced agranulocytosis. A protective tracheostomy, prophylactic thyroidectomy, serial surgical debridement, and broad-spectrum antibiotics therapy were initiated. Our team referred the patient for subsequent soft tissue reconstruction. Reconstruction was challenging as it involved a full-thickness cheek defect extending to the oral commissure, lower lip, and anterior neck. In a single-stage procedure, we utilised a transverse upper gracilis free flap to reconstruct full-thickness tissue loss, provide tissue bulk, and seal the dead space. Reconstructing various parts of the face and lips while ensuring aesthetic and functional results can be difficult..
坏死性筋膜炎(NF)是一种罕见、严重、进展迅速且危及生命的协同感染,主要累及浅筋膜。虽然在头颈外科手术中并不常见,但坏死性筋膜炎可能会产生严重后果。牙齿问题、烧伤、创伤和扁桃体周围脓肿常引发此病。我们描述了一例罕见的因卡比马唑诱发粒细胞缺乏症继发广泛面部坏死性筋膜炎的病例。实施了保护性气管切开术、预防性甲状腺切除术、系列外科清创术及广谱抗生素治疗。我们的团队将患者转诊以进行后续的软组织重建。重建颇具挑战性,因为其涉及延伸至口角、下唇和前颈部的全层脸颊缺损。在一期手术中,我们采用横行股薄肌游离皮瓣来重建全层组织缺损、提供组织量并封闭死腔。在确保美观和功能效果的同时重建面部和嘴唇的各个部位可能会很困难。