Yingxiao Cao, Hao Wang, Shuling Shang, Xike Zhang, Qingye Feng
Department of Neurosurgery, Xingtai People's Hospital Affiliated to Hebei Medical University, Xingtai, China.
Front Surg. 2025 May 16;12:1575229. doi: 10.3389/fsurg.2025.1575229. eCollection 2025.
Intracranial chondromas are exceedingly rare neoplasms, accounting for 0.2% to 0.3% of all intracranial tumors. These tumors predominantly originate from the skull base, particularly at the cartilaginous junctions of the cranial sutures, with the sella turcica being the most common site.
Between April 2022 and August 2023, the Department of Neurosurgery at Xingtai People's Hospital Affiliated to Hebei Medical University treated two cases of giant skull base chondromas using endoscopic extended endonasal resection. Near-total resection was achieved, and postoperative histopathological examination confirmed the diagnosis of chondroma. Both patients recovered well postoperatively.
Skull base chondromas are deeply seated and often involve extensive regions. Complete surgical resection remains the greatest challenge and the most critical factor influencing prognosis.selecting the appropriate surgical approach and achieving complete endoscopic resection can effectively prevent tumor recurrence and improve patient quality of life.
颅内软骨瘤是极为罕见的肿瘤，占所有颅内肿瘤的0.2%至0.3%。这些肿瘤主要起源于颅底，特别是在颅缝的软骨交界处，蝶鞍是最常见的部位。
2022年4月至2023年8月期间，河北医科大学附属邢台市人民医院神经外科采用内镜扩大经鼻切除术治疗了2例巨大颅底软骨瘤。实现了近全切除，术后组织病理学检查确诊为软骨瘤。两名患者术后恢复良好。
颅底软骨瘤位置深，常累及广泛区域。完整的手术切除仍然是最大的挑战，也是影响预后的最关键因素。选择合适的手术入路并实现完整的内镜切除可有效预防肿瘤复发并提高患者生活质量。
