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前壁心肌梗死伴严重传导障碍:一种值得铭记的罕见表现。

Severe Conduction Disturbances Accompanying Anterior Wall Myocardial Infarction: An Infrequent Presentation to Remember.

作者信息

Mallol-Simmonds Manuel, Fuentes-Garrido Rocio, Villarroel Alfredo, Valenzuela Catalina, Llancaqueo Marcelo

机构信息

Cardiovascular Investigation Unit, University of Chile's Clinical Hospital, Santiago, Chile.

Faculty of Medicine, University of Chile, Santiago, Chile.

出版信息

Case Rep Cardiol. 2025 May 24;2025:8331292. doi: 10.1155/cric/8331292. eCollection 2025.

DOI:10.1155/cric/8331292
PMID:40453463
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12126253/
Abstract

Anterior ST-elevation myocardial infarction (STEMI) is frequently associated with severe complications, such as myocardial dysfunction and conduction abnormalities. Complete atrioventricular block (CAVB), especially when combined with bifascicular block, is a rare but critical presentation that reflects extensive myocardial damage, often linked to proximal left anterior descending (LAD) artery occlusion. A 76-year-old male with a history of hypertension, diabetes mellitus, and dyslipidemia presented to the emergency department with a 6-day history of gastrointestinal symptoms and recurrent syncope. On arrival, he exhibited bradycardia, hypotension, and mottling, progressing to cardiac arrest. The return of spontaneous circulation was achieved after one cycle of advanced cardiovascular life support. Electrocardiography revealed CAVB with a ventricular escape rhythm displaying right bundle branch block morphology, left anterior fascicular block, and anterior ST-segment elevation. Emergency interventions included endotracheal intubation, Swan-Ganz catheterization, transvenous pacing, and vasopressor support. Echocardiography demonstrated severe left ventricular systolic dysfunction with an ejection fraction of 25%. Coronary angiography identified critical proximal stenoses in the LAD and circumflex arteries, managed with percutaneous coronary intervention and stent placement. Persistent conduction abnormalities and systolic dysfunction necessitated implantation of a cardiac resynchronization therapy defibrillator (CRT-D). Despite extensive rehabilitation efforts, the patient died after 60 days of hospitalization. This case highlights the importance of rapid recognition and intervention in anterior STEMI complicated by CAVB and bifascicular block, signaling significant proximal LAD involvement. Advanced therapeutic options, including CRT-D, are crucial for addressing these rare, life-threatening conduction disturbances. The fatal outcome underscores the need for vigilant follow-up and individualized preventive strategies to improve prognosis in such complex STEMI cases.

摘要

前壁ST段抬高型心肌梗死(STEMI)常伴有严重并发症,如心肌功能障碍和传导异常。完全性房室传导阻滞(CAVB),尤其是合并双分支阻滞时,是一种罕见但危急的表现,反映了广泛的心肌损伤,常与左前降支(LAD)近端闭塞有关。一名76岁男性,有高血压、糖尿病和血脂异常病史,因6天的胃肠道症状和反复晕厥就诊于急诊科。入院时,他表现为心动过缓、低血压和皮肤花斑,随后进展为心脏骤停。经过一个周期的高级心血管生命支持后恢复了自主循环。心电图显示CAVB,伴有心室逸搏心律,呈右束支阻滞形态、左前分支阻滞和前壁ST段抬高。紧急干预措施包括气管插管、 Swan-Ganz导管插入术、经静脉起搏和血管升压药支持。超声心动图显示严重的左心室收缩功能障碍,射血分数为25%。冠状动脉造影显示LAD和回旋支近端严重狭窄,通过经皮冠状动脉介入治疗和支架置入进行处理。持续的传导异常和收缩功能障碍需要植入心脏再同步化治疗除颤器(CRT-D)。尽管进行了广泛的康复努力,患者在住院60天后死亡。 本病例强调了对合并CAVB和双分支阻滞的前壁STEMI进行快速识别和干预的重要性,表示LAD近端有明显受累。包括CRT-D在内的高级治疗选择对于解决这些罕见的、危及生命的传导障碍至关重要。致命的结果强调了对此类复杂STEMI病例进行密切随访和个体化预防策略以改善预后的必要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/292e/12126253/deaeb9d5e170/CRIC2025-8331292.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/292e/12126253/def7dbc63664/CRIC2025-8331292.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/292e/12126253/deaeb9d5e170/CRIC2025-8331292.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/292e/12126253/def7dbc63664/CRIC2025-8331292.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/292e/12126253/deaeb9d5e170/CRIC2025-8331292.002.jpg

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本文引用的文献

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