Li Yan, Li Xiaomei, Huang Jingwen, Cai Hejia
College of Physical Education and Health, Guangxi Normal University, Guilin, China.
Department of Physical Education, Guilin University of Aerospace Technology, Guilin, China.
Front Public Health. 2025 May 12;13:1570878. doi: 10.3389/fpubh.2025.1570878. eCollection 2025.
Post-stroke depression (PSD) is a common complication that worsens neurological recovery and increases mortality among stroke survivors, creating a significant burden on patients and families. While exercise interventions are known to alleviate depressive symptoms in mild stroke cases, the effects of traditional Chinese exercises on PSD have not been systematically reviewed. This study aimed to evaluate the clinical efficacy of traditional Chinese exercises in treating PSD. A comprehensive search of eight Chinese and English databases identified randomized controlled trials (RCTs) published up to July 2024. Data were independently screened, extracted, and analyzed using RevMan 5.3 and Stata 17, with heterogeneity assessed through sensitivity, subgroup, and meta-regression analyses. Ten RCTs involving 627 participants were included. Meta-analysis revealed that traditional Chinese exercises significantly reduced depressive symptoms and improved daily living abilities in PSD patients. Specifically, HAMD scores decreased [SMD = -1.40, 95% CI (-1.88, -0.92), < 0.00001], treatment efficacy improved [OR = 3.74, 95% CI (1.69, 8.28), = 0.001], FMA scores increased [MD = 6.22, 95% CI (4.12, 8.32), < 0.00001], and BI levels rose [MD = 4.95, 95% CI (2.96, 6.93), < 0.00001]. In conclusion, traditional Chinese exercises offer significant benefits in treating PSD, demonstrating both efficacy and safety. https://www.crd.york.ac.uk/PROSPERO/view/CRD42024574791.
中风后抑郁（PSD）是一种常见的并发症，会使神经功能恢复恶化，并增加中风幸存者的死亡率，给患者及其家庭带来沉重负担。虽然运动干预已知可缓解轻度中风病例中的抑郁症状，但传统中医运动对PSD的影响尚未得到系统评价。本研究旨在评估传统中医运动治疗PSD的临床疗效。对八个中英文数据库进行全面检索，确定截至2024年7月发表的随机对照试验（RCT）。使用RevMan 5.3和Stata 17对数据进行独立筛选、提取和分析，并通过敏感性、亚组和meta回归分析评估异质性。纳入了10项涉及627名参与者的RCT。meta分析显示，传统中医运动显著减轻了PSD患者的抑郁症状，提高了日常生活能力。具体而言，汉密尔顿抑郁量表（HAMD）评分降低[标准化均数差（SMD）=-1.40，95%置信区间（-1.88，-0.92），P<0.00001]，治疗效果改善[比值比（OR）=3.74，95%置信区间（1.69，8.28），P=0.001]，Fugl-Meyer评估量表（FMA）评分增加[平均差（MD）=6.22，95%置信区间（4.12，8.32），P<0.00001]，Barthel指数（BI）水平升高[MD=4.95，95%置信区间（2.96，6.93），P<0.00001]。总之，传统中医运动在治疗PSD方面具有显著益处，显示出有效性和安全性。https://www.crd.york.ac.uk/PROSPERO/view/CRD42024574791
