Alqaissi Nesreen
Nursing Faculty, Palestine Polytechnic University, Hebron, Palestine.
SAGE Open Nurs. 2025 May 30;11:23779608251347119. doi: 10.1177/23779608251347119. eCollection 2025 Jan-Dec.
Central line-associated bloodstream infections (CLABSI) are a significant source of hospital-acquired infections, particularly in intensive care units where central venous catheters are frequently used. These infections can lead to increased morbidity, mortality, and healthcare costs. While various clinical guidelines exist for prevention, the actual knowledge and adherence of nurses to these guidelines vary widely, with limited synthesis available at the systematic review level.
This study aimed to synthesize current evidence on the knowledge, behaviors, and adherence of intensive care unit nurses regarding CLABSI prevention practices.
This systematic review was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Peer-reviewed empirical studies published between 2018 and 2024 were searched in PubMed, Scopus, and Google Scholar. Studies were included if they assessed ICU nurses' knowledge and practices related to CLABSI prevention. After screening 3,585 articles, nine studies met the inclusion criteria and were appraised using the Risk of Bias in Systematic Reviews (ROBIS) tool.
Nine full-text studies published between 2018 and 2024 were analyzed. The studies used cross-sectional surveys, cohort designs, and questionnaire validation methods. Most nurses demonstrated moderate knowledge levels, but adherence to prevention guidelines was low, with full compliance reported by only 5% of participants. Key themes included training gaps, institutional variability, and increased infection risk from improper catheter use. Several studies suggested that targeted education and the use of diagnostic tools such as procalcitonin may support improved outcomes.
This review highlights a persistent gap between knowledge and adherence to CLABSI prevention practices among ICU nurses. Strengthening education, institutional support, and diagnostic strategies is essential to reduce infection rates and improve patient safety.
中心静脉导管相关血流感染（CLABSI）是医院获得性感染的重要来源，尤其是在经常使用中心静脉导管的重症监护病房。这些感染会导致发病率、死亡率上升以及医疗成本增加。虽然存在各种预防的临床指南，但护士对这些指南的实际了解和遵守情况差异很大，在系统评价层面上的综合研究有限。
本研究旨在综合当前关于重症监护病房护士在CLABSI预防实践方面的知识、行为和遵守情况的证据。
本系统评价按照系统评价和Meta分析的首选报告项目（PRISMA）指南进行。在PubMed、Scopus和谷歌学术上检索了2018年至2024年间发表的同行评审实证研究。如果研究评估了ICU护士与CLABSI预防相关的知识和实践，则纳入研究。在筛选了3585篇文章后，9项研究符合纳入标准，并使用系统评价中的偏倚风险（ROBIS）工具进行评估。
分析了2018年至2024年间发表的9项全文研究。这些研究采用了横断面调查、队列设计和问卷验证方法。大多数护士表现出中等知识水平，但对预防指南的遵守程度较低，只有5%的参与者报告完全遵守。关键主题包括培训差距、机构差异以及导管使用不当导致的感染风险增加。几项研究表明，有针对性的教育以及使用降钙素原等诊断工具可能有助于改善结果。
本综述强调了ICU护士在CLABSI预防实践的知识和遵守方面存在持续差距。加强教育以及机构支持和诊断策略对于降低感染率和提高患者安全至关重要。
