Seid A B, Canty T G
J Pediatr Surg. 1985 Aug;20(4):388-90. doi: 10.1016/s0022-3468(85)80224-4.
Severe acquired subglottic stenosis occurs most commonly in infants and children who require long-term ventilatory support with indwelling endotracheal tubes for underlying respiratory disease. A variety of operative and endoscopic procedures have been advocated for this problem including endoscopic fulguration, cryotherapy, direct incision or excision, and several types of extensive direct laryngotracheoplasties. The failure rate with these procedures is high. We have treated 22 patients including 12 neonates and 10 older children with acquired airway injury and obstruction with a simple cricoid split. In 15 patients the airway obstruction was completely relieved and these youngsters were extubated without difficulty. An additional 3 patients failed initial extubation which was subsequently successful, however, after repeat intubation for a short period of time. Endoscopic follow-up shows complete healing of the incised area. In 2 neonates the procedure was unsuccessful, and tracheotomy was needed. One of these had additional severe airway injury in the distal tracheobronchial tree secondary to selective bronchial intubation in the newborn period. Two older children also required tracheotomy because of severe airway scarring unrelieved by this procedure. The cricoid split is a simple and successful way of dealing with subglottic stenosis, especially in the newborn premature infant. A significant advantage is that it disturbs the anatomy very little, allowing for more extensive laryngotracheoplasty in the future should it fail.
严重获得性声门下狭窄最常见于因潜在呼吸系统疾病需要长期使用留置气管插管进行通气支持的婴幼儿。针对这个问题,人们提出了多种手术和内镜治疗方法,包括内镜电灼、冷冻疗法、直接切开或切除,以及几种类型的广泛直接喉气管成形术。这些治疗方法的失败率很高。我们用简单的环状软骨劈开术治疗了22例患者,其中包括12例新生儿和10例大龄儿童,他们均有获得性气道损伤和梗阻。15例患者的气道梗阻完全解除,这些患儿顺利拔管。另外3例患者初次拔管失败,但在短时间再次插管后拔管成功。内镜随访显示切开区域完全愈合。2例新生儿手术失败,需要进行气管切开术。其中1例在新生儿期因选择性支气管插管继发远端气管支气管树严重气道损伤。2例大龄儿童也因该手术未能缓解的严重气道瘢痕而需要气管切开术。环状软骨劈开术是治疗声门下狭窄的一种简单且成功的方法,尤其适用于早产新生儿。一个显著的优点是它对解剖结构的干扰很小,如果失败,未来还可以进行更广泛的喉气管成形术。