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去上皮游离穿支皮瓣在慢性跟骨骨髓炎同期骨与软组织重建中的应用

Use of de-epithelialized free perforator flaps for simultaneous bone and soft-tissue reconstruction in chronic calcaneus osteomyelitis.

作者信息

Park Bo Young

机构信息

Department of Plastic and Reconstructive Surgery, School of Medicine, Ewha Womans University, Seoul, Republic of Korea.

出版信息

Sci Rep. 2025 Jun 2;15(1):19264. doi: 10.1038/s41598-025-04007-2.

Abstract

Treating chronic calcaneal osteomyelitis (OM) is complex and challenging. After aggressive surgical debridement of the infected tissue, filling the bone's dead space and covering the defect may be necessary. This study describes the successful treatment of chronic calcaneal OM using a de-epithelialized perforator flap to reconstruct soft-tissue and bone defects simultaneously. The study retrospectively reviewed the medical records of 10 patients diagnosed with Cierny-Mader type III-IV calcaneus OM treated with de-epithelialized free perforator flaps between 2015 and 2023. The data included patient demographics (age, sex, and comorbidities), OM duration, perforator flap type, intraoperative and postoperative complications, flap survival, additional surgical interventions, OM recurrence, and functional outcomes. The American Orthopedic Foot and Ankle Society ankle and hindfoot scale was used to assess the functional results 6 months after surgery. The study included 10 patients with a mean age of 49.2 years (range: 29-62 years). The average OM duration before surgical intervention was 18 months (range: 11-24 months). Flap​ ​survival​ ​was​ ​90%,​ ​with​ ​one​ ​case​ ​of​ ​partial​ ​necrosis​ ​requiring​ ​secondary​ ​full-thickness​ ​skin​ ​grafting. No OM recurrence was observed during the follow-up period, except for minor wounds in the weight-bearing region. Perforator flaps offer a viable option for obliterating dead space in cases where chronic infection compromises the blood supply in chronic OM. A thinned de-epithelialized perforator flap supports a multidisciplinary approach for managing chronic calcaneal OM, balancing the amount of surgical intervention with functional preservation and infection control.

摘要

治疗慢性跟骨骨髓炎(OM)复杂且具有挑战性。在对感染组织进行积极的手术清创后,可能需要填充骨的死腔并覆盖缺损。本研究描述了使用去上皮穿支皮瓣同时重建软组织和骨缺损成功治疗慢性跟骨OM的案例。该研究回顾性分析了2015年至2023年间10例诊断为Cierny-Mader III-IV型跟骨OM并接受去上皮游离穿支皮瓣治疗的患者的病历。数据包括患者人口统计学信息(年龄、性别和合并症)、OM病程、穿支皮瓣类型、术中及术后并发症、皮瓣存活情况、额外的手术干预、OM复发情况以及功能结局。采用美国矫形足踝协会的踝与后足评分量表在术后6个月评估功能结果。该研究纳入了10例患者,平均年龄49.2岁(范围:29 - 62岁)。手术干预前OM的平均病程为18个月(范围:11 - 24个月)。皮瓣存活率为90%,1例部分坏死需要二期全厚皮片移植。随访期间未观察到OM复发,除了负重区域有小伤口。在慢性感染损害慢性OM血供的情况下,穿支皮瓣为消除死腔提供了一种可行选择。去上皮变薄的穿支皮瓣支持采用多学科方法管理慢性跟骨OM,在手术干预量与功能保留和感染控制之间取得平衡。

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