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[下肢关节损伤骨科内固定术后切口感染的临床治疗探讨]

[Exploration on clinical treatment of incisional wound infection after orthopedic internal fixation for lower extremity joint injuries].

作者信息

Du W L, Shen Y M, Hu X H, Cheng L

机构信息

Department of Burns, Beijing Jishuitan Hospital, Beijing 100035, China.

出版信息

Zhonghua Shao Shang Za Zhi. 2021 Mar 20;37(3):216-224. doi: 10.3760/cma.j.cn501120-20201108-00463.

Abstract

To explore the clinical treatment of incisional wound infection after orthopedic internal fixation for lower extremity joint injuries. A retrospective cohort study was conducted. From February 2014 to December 2019, 214 patients with lower limb closed injury were treated in Beijing Jishuitan Hospital, including 143 males and 71 females, aged from 16 to 65 years. All patients underwent orthopedic internal fixation, after which incisional wound infection developed in 42 cases of postoperative wounds of patellar fracture, 30 cases of postoperative wounds of tibial plateau fracture, 72 cases of postoperative wounds of Achilles tendon rupture, 45 cases of postoperative wounds of calcaneal fracture, and 25 cases of postoperative wounds of Pilon fracture with 31 cases of superficial infection and 183 cases of deep infection. According to the postoperative evaluation of the incisional wounds, dressing change and/or thorough debridement (with wound area from 4 cm×3 cm to 11 cm×5 cm after debridement), and internal fixation treatment were performed. After thorough debridement, wounds were treated with continuous vacuum sealing drainage (VSD), and then direct suture+VSD or flap transplantation were performed according to the incision and its surrounding skin tissue, infection, suture tension, exposure of internal fixation or bone or Achilles tendon tissue. According to the wound site and injury, the flap types of retrograde anterolateral thigh perforator flap, medial sural artery perforator flap, gastrocnemius myocutaneous flap, sural neurovascular flap, peroneal brevis muscle flap, posterior tibial artery perforator flap, and free anterolateral thigh perforator flap could be selected. The donor site wound was closed by direct suture or grafted with split-thickness skin graft. The removal of internal fixation, wound repair method, type and size of flaps, survival of flaps, and wound healing were recorded. The recurrence of infection, appearance of donor and recipient areas, and recovery of lower limb joint function were followed up. All the internal fixations were removed in patients with postoperative wounds of patellar fracture, among whom 36 cases were repaired with retrograde anterolateral thigh perforator flap, and 6 cases were repaired with medial sural artery perforator flap. Among the patients with postoperative wounds of tibial plateau fracture, the internal fixation was completely retained in 18 cases, partially removed in 6 cases, and completely removed in 6 cases, while the wound was closed by direct suture in 8 cases, transplanted with gastrocnemius myocutaneous flap in 21 cases, and transplanted with medial sural artery perforator flap in 1 case. Among the patients with postoperative wounds of Achilles tendon rupture, the internal fixation was completely retained in 10 cases and completely removed in 62 cases, and the wound was closed by direct suture in 10 cases and transplanted with sural neurovascular flap in 62 cases. Among the patients with postoperative wounds of calcaneal fracture, the internal fixation was completely removed in 32 cases and completely retained in 13 cases, and the wound was healed by dressing change in 5 cases, closed by direct suture in 5 cases, transplanted with sural neurovascular flap in 23 cases, and transplanted with sural neurovascular flap combined with peroneal brevis muscle flap in 12 cases. Among the patients with postoperative wounds of Pilon fracture, the internal fixation was partially removed in 5 cases, completely retained in 17 cases, and completely removed in 3 cases; the wound was closed by direct suture in 4 cases, transplanted with posterior tibial artery perforator flap in 18 cases, and transplanted with free anterolateral thigh flap in 3 cases. The area of flaps/myocutaneous flaps ranged from 5 cm×3 cm to 18 cm×8 cm, and the area of muscle flaps were from 13.0 cm×1.5 cm to 15.0 cm×2.5 cm. All the wounds closed by direct suture healed. Blood flow obstacle occurred in the distal margin of sural neurovascular flap transplanted in 5 patients and posterior tibial artery perforator flap transplanted in one patient, which healed successfully after dressing change. The other flaps survived well, and the wounds were healed. The patients were followed up for 5 months to 5 years, and no recurrence of infection occurred. The direct suture of the flap donor site left linear scar, and the appearance of the skin graft was good. Three patients with tibial plateau fracture and 2 patients with Pilon fracture had limited joint movement, while the joint activity of the other patients was normal. The patients with Achilles tendon rupture and calcaneal fracture had normal ground motion. The sural neurovascular flap grafted on the wound after calcaneal fracture was bloated resulting in inconvenience in wearing shoes, the gastrocnemius myocutaneous flap grafted on the postoperative wound after tibial plateau fracture was bloated, whereas the appearance of the other flaps was good. For incisional wound infection after orthopedic internal fixation for lower extremity joint injuries, the treatment should be classified according to wound infection and wound site. Dressing change, thorough debridement, reasonable disposal of internal fixation, direct suture after application of VSD, and flap covering, etc. not only ensure the infection control and the wound closure, but also restore the function of the lower limbs to the greatest extent, so as to maximize the benefit of the patient.

摘要

探讨下肢关节损伤骨科内固定术后切口感染的临床治疗方法。进行一项回顾性队列研究。2014年2月至2019年12月,北京积水潭医院收治214例下肢闭合性损伤患者,其中男性143例,女性71例,年龄16至65岁。所有患者均接受骨科内固定治疗,术后切口感染发生于髌骨骨折术后伤口42例、胫骨平台骨折术后伤口30例、跟腱断裂术后伤口72例、跟骨骨折术后伤口45例、Pilon骨折术后伤口25例,其中浅表感染31例,深部感染183例。根据术后切口评估情况,进行换药和/或彻底清创(清创后伤口面积为4 cm×3 cm至11 cm×5 cm)以及内固定处理。彻底清创后,伤口采用持续封闭式负压引流(VSD)治疗,然后根据切口及其周围皮肤组织、感染情况、缝合张力、内固定或骨质或跟腱组织暴露情况,进行直接缝合+VSD或皮瓣移植。根据伤口部位和损伤情况,可选用逆行股前外侧穿支皮瓣、腓肠内侧动脉穿支皮瓣、腓肠肌肌皮瓣、腓肠神经营养血管皮瓣、腓骨短肌肌瓣、胫后动脉穿支皮瓣、游离股前外侧穿支皮瓣等皮瓣类型。供区伤口采用直接缝合或植皮封闭。记录内固定取出情况、伤口修复方法、皮瓣类型及大小、皮瓣成活情况及伤口愈合情况。随访感染复发情况、供区和受区外观及下肢关节功能恢复情况。髌骨骨折术后伤口患者均取出内固定,其中36例采用逆行股前外侧穿支皮瓣修复,6例采用腓肠内侧动脉穿支皮瓣修复。胫骨平台骨折术后伤口患者中,18例完全保留内固定,6例部分取出内固定,6例完全取出内固定,8例伤口直接缝合,21例移植腓肠肌肌皮瓣,1例移植腓肠内侧动脉穿支皮瓣。跟腱断裂术后伤口患者中,10例完全保留内固定,62例完全取出内固定,10例伤口直接缝合,62例移植腓肠神经营养血管皮瓣。跟骨骨折术后伤口患者中,32例完全取出内固定,13例完全保留内固定,5例通过换药愈合,5例直接缝合,23例移植腓肠神经营养血管皮瓣,12例移植腓肠神经营养血管皮瓣联合腓骨短肌肌瓣。Pilon骨折术后伤口患者中,5例部分取出内固定,17例完全保留内固定,3例完全取出内固定;4例伤口直接缝合,18例移植胫后动脉穿支皮瓣,3例移植游离股前外侧皮瓣。皮瓣/肌皮瓣面积为5 cm×3 cm至18 cm×8 cm,肌瓣面积为13.0 cm×1.5 cm至15.0 cm×2.5 cm。所有直接缝合的伤口均愈合。5例移植腓肠神经营养血管皮瓣及1例移植胫后动脉穿支皮瓣患者出现皮瓣远端边缘血流障碍,经换药后愈合。其他皮瓣成活良好,伤口愈合。患者随访5个月至5年,无感染复发。皮瓣供区直接缝合遗留线状瘢痕,植皮外观良好。3例胫骨平台骨折患者及2例Pilon骨折患者关节活动受限,其余患者关节活动正常。跟腱断裂和跟骨骨折患者下地活动正常。跟骨骨折伤口移植腓肠神经营养血管皮瓣后肿胀,穿鞋不便,胫骨平台骨折术后伤口移植腓肠肌肌皮瓣后肿胀,其余皮瓣外观良好。对于下肢关节损伤骨科内固定术后切口感染,应根据伤口感染情况及伤口部位进行分类治疗。换药、彻底清创、合理处理内固定、应用VSD后直接缝合、皮瓣覆盖等,既能保证感染控制和伤口闭合,又能最大程度恢复下肢功能,使患者获益最大化。

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