Hänel I, Liebermann B, Brückner B, Tröger R
J Basic Microbiol. 1985;25(6):365-71. doi: 10.1002/jobm.3620250603.
The effect of the cosubstrate acetate on the formation of the phytotoxic substance tentoxin by Alternaria alternata (Fr.) Keissler was investigated. Acetate was taken up and metabolized during growth. The added acetate stimulated considerably the biosynthesis of tentoxin depending on its concentration and time of introduction. There was an increased incorporation of (U-14C)-glucose into the toxin molecule in the presence of acetate in the medium. The results indicate an induction of the biosynthesis of tentoxin by the precursor acetate, probably mediated through the accumulation of the glycolytic intermediates pyruvate and phosphoenolpyruvate.
研究了共底物乙酸盐对链格孢菌(Alternaria alternata (Fr.) Keissler)产生植物毒性物质细交链孢菌酮酸的影响。在生长过程中,乙酸盐被吸收并代谢。添加的乙酸盐根据其浓度和引入时间显著刺激了细交链孢菌酮酸的生物合成。在培养基中存在乙酸盐的情况下,(U-14C)-葡萄糖掺入毒素分子的量增加。结果表明,前体乙酸盐诱导了细交链孢菌酮酸的生物合成,可能是通过糖酵解中间产物丙酮酸和磷酸烯醇丙酮酸的积累介导的。