Johnson Kayla T, Zawadzki Matthew J, Widome Rachel, Kavanaugh Melinda S
Division of Epidemiology and Community Health, University of Minnesota, Minneapolis, MN, United States.
Department of Psychology, University of Wisconsin-Milwaukee, Milwaukee, WI, United States.
Int J Behav Med. 2025 Jun 2. doi: 10.1007/s12529-025-10374-x.
Migraine is the second most disabling illness in the world. Research has largely focused on pharmacological treatments, with limited studies evaluating behavioral interventions. The aim of this study was to evaluate the acceptability of a novel behavioral intervention targeting exercise and sleep among sedentary people with migraine.
Nineteen participants engaged in a randomized controlled trial assigned to either a phone-delivered educational intervention for best sleep practices and exercise tailored to people with migraine or a no-treatment control group. Participants tracked their migraine frequency, duration, intensity, sleep, and physical activity using ecological momentary assessment over a 4-week study period. Depression, anxiety, and quality of life were measured pre- and post-intervention.
Results showed 93% and 94% adherence to the ecological momentary assessment procedure and exercise intervention, respectively, with 57.1 more minutes of physical activity in week 2 [CI 51.4, 62.7], 57.7 in week 3 [CI 52.0, 63.3], and 56.6 in week 4 [CI 50.9, 62.2], compared to week 1 for the intervention group. Preliminary efficacy results showed sleep duration improved over time for the intervention group, with 0.77 more hours in week 3 [0.22, 1.31] and 0.95 more hours in week 4 [0.40, 1.49], compared to baseline. Anxiety symptoms significantly decreased over time for the intervention group compared to the control group (p < .021, d = 0.25). Other results were null.
This study demonstrates the acceptability of a multicomponent lifestyle intervention, suggesting its potential for large-scale implementation to address behavioral and psychological comorbidities in migraine management.
偏头痛是世界上第二大致残性疾病。研究主要集中在药物治疗上,评估行为干预的研究有限。本研究的目的是评估一种针对久坐的偏头痛患者的运动和睡眠的新型行为干预的可接受性。
19名参与者进行了一项随机对照试验,分为两组,一组接受通过电话提供的针对偏头痛患者的最佳睡眠习惯和运动的教育干预,另一组为无治疗对照组。在为期4周的研究期间,参与者使用生态瞬时评估法记录他们的偏头痛频率、持续时间、强度、睡眠和身体活动情况。在干预前后测量抑郁、焦虑和生活质量。
结果显示,分别有93%和94%的参与者坚持生态瞬时评估程序和运动干预,与第1周相比,干预组在第2周的身体活动增加了57.1分钟[可信区间51.4, 62.7],第3周增加了57.7分钟[可信区间52.0, 63.3],第4周增加了56.6分钟[可信区间50.9, 62.2]。初步疗效结果显示,干预组的睡眠时间随时间改善,与基线相比,第3周增加了0.77小时[0.22, 1.31],第4周增加了0.95小时[0.40, 1.49]。与对照组相比,干预组的焦虑症状随时间显著减少(p <.021,d = 0.25)。其他结果均无统计学意义。
本研究证明了一种多成分生活方式干预的可接受性,表明其在偏头痛管理中大规模实施以解决行为和心理合并症的潜力。