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股前外侧游离皮瓣修复坏疽性口炎面部后遗症:两例报告

Reconstruction facial sequelaes of NOMA with anterolateral thigh free flap: two case reports.

作者信息

Nghĩa Phan Tuấn, Sơn Trần Thiết, Dung Phạm Thị Việt, Thuý Tạ Thị Hồng, Nam Đặng Phương, Linh Lê Diệp

机构信息

Department of Plastic and Reconstructive Surgery, Hanoi Medical University, No. 1 Ton That Tung, Kim Lien, Dong Da, Ha Noi, 116177, Hanoi, Vietnam.

Department of Plastic Reconstructive and Aesthetic Surgery, Bach Mai Hospital, No. 78 Giai Phong, Phuong Dinh, Dong Da, Ha Noi, 11500, Hanoi, Vietnam.

出版信息

J Surg Case Rep. 2025 Jun 2;2025(6):rjaf354. doi: 10.1093/jscr/rjaf354. eCollection 2025 Jun.

DOI:10.1093/jscr/rjaf354
PMID:40458239
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12129103/
Abstract

NOMA, or oral labial necrosis, is a severe condition characterized by significant facial tissue destruction and elevated mortality rates, particularly in developing regions. Survivors often experience significant long-term consequences, leading to both functional and aesthetic impairments. The reconstruction of NOMA sequelae poses considerable challenges, including issues related to volume deficits, bone defects, and contracture deformities. This report presents two cases in which chimeric anterolateral thigh (ALT) flaps were effectively applied to address complex defects. The versatility of the ALT flap facilitated the reconstruction of multiple components, encompassing skin coverage, volume augmentation, and mucosal lining. This methodology offers a single-stage solution for reconstructing intricate NOMA sequelae, resulting in favorable functional and aesthetic outcomes.

摘要

走马疳,即口腔唇部坏死,是一种严重病症,其特征为面部组织严重受损且死亡率高,在发展中地区尤为如此。幸存者往往会面临严重的长期后果,导致功能和美观方面的损害。走马疳后遗症的重建面临诸多挑战,包括体积不足、骨缺损和挛缩畸形等问题。本报告介绍了两例应用嵌合型股前外侧(ALT)皮瓣有效解决复杂缺损的病例。ALT皮瓣的多功能性有助于重建多个部位,包括皮肤覆盖、体积增大和黏膜内衬。这种方法为重建复杂的走马疳后遗症提供了单阶段解决方案,产生了良好的功能和美学效果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f9bf/12129103/0a7301d40746/rjaf354f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f9bf/12129103/2eddab22888b/rjaf354f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f9bf/12129103/0a7301d40746/rjaf354f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f9bf/12129103/2eddab22888b/rjaf354f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f9bf/12129103/0a7301d40746/rjaf354f2.jpg

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本文引用的文献

1
Reconstruction of Noma Sequelae: A Surgical Treatment Algorithm Developed from Lessons from 210 Cases in Ethiopia.坏疽性口炎后遗症的重建:基于埃塞俄比亚210例病例经验制定的手术治疗方案
Plast Reconstr Surg Glob Open. 2023 Mar 6;11(3):e4844. doi: 10.1097/GOX.0000000000004844. eCollection 2023 Mar.
2
Microvascular reconstruction of facial defects in settings where resources are limited.资源有限情况下面部缺损的微血管重建
Br J Oral Maxillofac Surg. 2016 Jan;54(1):51-6. doi: 10.1016/j.bjoms.2015.10.020. Epub 2015 Nov 19.
3
Reconstruction of complex oro-facial defects using the myocutaneous sub-mental artery flap.
应用颏下动脉肌皮瓣修复复杂口腔颌面部缺损
J Craniomaxillofac Surg. 2014 Jul;42(5):668-73. doi: 10.1016/j.jcms.2013.09.013. Epub 2013 Sep 30.
4
The expanding role of the anterolateral thigh free flap in head and neck reconstruction.股前外侧游离皮瓣在头颈部重建中不断扩大的作用。
Curr Opin Otolaryngol Head Neck Surg. 2011 Aug;19(4):263-8. doi: 10.1097/MOO.0b013e328347f845.
5
Reconstruction of the maxilla with prefabricated scapular flaps in noma patients.用预制肩胛皮瓣修复走马疳患者的上颌骨
Plast Reconstr Surg. 2008 Jun;121(6):1964-1973. doi: 10.1097/PRS.0b013e3181706dd6.
6
The use of the pedicled supraclavicular flap in noma reconstructive surgery.带蒂锁骨上皮瓣在坏疽性口炎重建手术中的应用。
J Plast Reconstr Aesthet Surg. 2006;59(4):337-42. doi: 10.1016/j.bjps.2005.10.005.
7
The free serratus anterior flap and its cutaneous component for reconstruction of the face: a series of 27 cases.游离前锯肌皮瓣及其皮瓣部分用于面部重建:27例系列报道
Plast Reconstr Surg. 2006 Apr;117(4):1277-88. doi: 10.1097/01.prs.0000208297.02556.a5.
8
Microsurgical reconstruction of noma-related facial defects with folded free flaps: an overview of 31 cases.采用折叠游离皮瓣对坏疽性口炎相关面部缺损进行显微外科重建:31例概述
Ann Plast Surg. 2005 Aug;55(2):132-8. doi: 10.1097/01.sap.0000165688.50780.e9.
9
The single and double-folded supraclavicular island flap as a new therapy option in the treatment of large facial defects in noma patients.单蒂和双蒂锁骨上岛状皮瓣作为治疗坏疽性口炎患者大面积面部缺损的一种新的治疗选择。
Plast Reconstr Surg. 2005 May;115(6):1591-6. doi: 10.1097/01.prs.0000160694.20881.f4.
10
Noma: an "infectious" disease of unknown aetiology.坏疽性口炎:一种病因不明的“传染性”疾病。
Lancet Infect Dis. 2003 Jul;3(7):419-31. doi: 10.1016/s1473-3099(03)00670-4.