Gupta Raghuveer Kumar, Niranjan Raghvendra, Baghel Kalpana, Sikdar Malabika
Fish Parasitology Lab, Department of Zoology, Dr. Harisingh Gour Vishwavidyalaya (A Central University), Sagar, M.P India.
Department of Microbiology, Dr Harisingh Gour Vishwavidyalaya (A Central University), Sagar, M.P India.
J Parasit Dis. 2025 Jun;49(2):433-446. doi: 10.1007/s12639-024-01772-1. Epub 2024 Dec 23.
Knowledge of the endemic parasite fauna in freshwater fish is of great importance. Parasites may work together to stress the health of their hosts. Therefore, the present study aimed to focus on the impact of nematode parasitism on () fish health. The objectives of the present study are to evaluate injury to tissues and oxidative damage due to parasitic infestation, which are indications of disturbance of fish health. According to the results of histological examination, the gut, liver, and gills from , infested with nematode parasites were among the organs severely damaged. Due to tissue injury and oxidative stress, malondialdehyde (MDA) levels were increased and disturbed the oxidant/antioxidant ratio. Enzymatic antioxidants like superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GPx) were significantly increased, but glutathione reductase (GR) and non-enzymatic antioxidant i.e., glutathione content (GSH) was significantly decreased. Thus, due to these histological alterations, antioxidant levels significantly affected the health of . Next, we also observed hematologically that, red blood cell (RBCs) and hemoglobin (Hb) levels and mineral content were decreased but white blood cells (WBCs) levels were increased. In liver, we have observed decreased protein, lipid as well as moisture, and ash content but there was an increase in the dry content and glucose levels. In serum biochemical parameters i.e., protein, albumin, globulin, and Albumin/Globulin (A/G) ratio was significantly decreased except glucose level (mg/dl). The increased glucose level may be due to the increase in the breakdown of liver glycogen or decreased synthesis of glycogen indicating the hyperglycemic condition in the infested fish. In conclusion, nematode species have a significant impact on the health status of the fish in culture practices.
了解淡水鱼体内的地方性寄生虫区系非常重要。寄生虫可能共同作用，对其宿主的健康造成压力。因此，本研究旨在关注线虫寄生对（）鱼类健康的影响。本研究的目的是评估由于寄生虫感染导致的组织损伤和氧化损伤，这些都是鱼类健康受到干扰的迹象。根据组织学检查结果，感染线虫寄生虫的（）的肠道、肝脏和鳃是受损严重的器官。由于组织损伤和氧化应激，丙二醛（MDA）水平升高，扰乱了氧化剂/抗氧化剂的比例。超氧化物歧化酶（SOD）、过氧化氢酶（CAT）和谷胱甘肽过氧化物酶（GPx）等酶促抗氧化剂显著增加，但谷胱甘肽还原酶（GR）和非酶促抗氧化剂即谷胱甘肽含量（GSH）显著降低。因此，由于这些组织学改变，抗氧化剂水平显著影响了（）的健康。接下来，我们还通过血液学观察发现，红细胞（RBCs）、血红蛋白（Hb）水平和矿物质含量降低，但白细胞（WBCs）水平升高。在肝脏中，我们观察到蛋白质、脂质以及水分和灰分含量降低，但干物质含量和葡萄糖水平升高。在血清生化参数方面，除葡萄糖水平（mg/dl）外，蛋白质、白蛋白、球蛋白和白蛋白/球蛋白（A/G）比值显著降低。葡萄糖水平升高可能是由于肝糖原分解增加或糖原合成减少，表明受感染鱼类出现高血糖状况。总之，线虫种类对养殖实践中鱼类的健康状况有显著影响。
